3507-62-8

Basic information

• Product Name: 2-AMYL SUCCINIC ACID
• Synonyms: 2-PENTYLSUCCINIC ACID;Heptane-1,2-dicarboxylic acid;2-AMYL SUCCINIC ACID
• CAS NO: 3507-62-8
• Molecular Formula: C₉H₁₆O₄
• Molecular Weight: 188.22
• Mol File: 3507-62-8.mol
• Article Data: 5

Chemical Properties

• Melting Point: 77 °C
• Boiling Point: 296.9±13.0 °C(Predicted)
• Appearance: /
• Density: 1.128±0.06 g/cm3(Predicted)
• PKA: 4.60±0.19(Predicted)
• CAS DataBase Reference: 2-AMYL SUCCINIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMYL SUCCINIC ACID(3507-62-8)
• EPA Substance Registry System: 2-AMYL SUCCINIC ACID(3507-62-8)

Safety Data

• Hazardous Substances Data: 3507-62-8(Hazardous Substances Data)

Usage

Uses

Used in Chemical Synthesis:
2-Amyl succinic acid is used as a building block in the chemical synthesis industry for the production of polymers, resins, and pharmaceuticals. Its ability to form stable linkages with other molecules makes it a valuable component in creating complex chemical structures.
Used in Fragrance and Flavor Industry:
In the fragrance and flavor industry, 2-Amyl succinic acid is utilized as an intermediate in the synthesis of various scents and tastes. Its unique chemical properties contribute to the development of novel and distinct sensory experiences.
Used in Pharmaceutical Development:
2-Amyl succinic acid has been studied for its potential biological and pharmacological activities, including anti-inflammatory and anti-cancer properties. It is used as a starting material in the development of new drugs that could address these health concerns.
Used in Polymer and Resin Production:
2-Amyl succinic acid is employed in the production of polymers and resins, where it contributes to the formation of materials with specific properties, such as durability, flexibility, and chemical resistance, which are essential in various applications across different industries.

Upstream product

• 105-39-5 chloroacetic acid ethyl ester 
• 6065-59-4 diethyl n-pentylmalonate 
• 110-62-3 pentanal 
• 865-47-4 potassium tert-butylate 
• 123-25-1 succinic acid diethyl ester 
• 110-53-2 1-Bromopentane 
• 7732-18-5 water 
• 3494-59-5 opt.inakt. 4-Ethoxy-4-hydroxy-2-pentyl-buttersaeure-lacton 
• 2624-01-3 2-bromoheptanoic acid 
• 149198-87-8 actinonin 
• 18294-96-7 ethyl 2-hydroxylheptanoate 
• 160295-85-2 (E)-dimethyl 2-pentylidene-1,4-butanedioate 
• 628-05-7 1-nitropentane 
• 38789-25-2 2-n-Pentyl-1,4-butanedioic acid dimethyl ester 

Downstream Products

• 38789-25-2 2-n-Pentyl-1,4-butanedioic acid dimethyl ester 
• 63120-94-5 (S)-(-)-2-pentylbutanedioic acid 
• 3975-91-5 (R)-(+)-2-pentylsuccinic acid 
• 46059-24-9 pentylsuccinic acid anhydride 

Relevant articles and documents

Nitroalkanes and dimethyl maleate as source of 3-alkyl succinic anhydrides and (E)-3-alkylidene succinic anhydrides

Nitroalkanes react with dimethyl maleate giving a tandem Michael addition/elimination of nitrous acid. The obtained (E)-2-alkylidene dimethyl succinates are: (i) reduced to the corresponding 2-alkyl dimethyl succinates which after hydrolysis produce 1,4-dicarboxylic acids that are prone to convert into the corresponding 3-alkyl succinic anhydrides or (ii) hydrolysed to (E)-2-alkylidene-succinic acids that are easily cyclised to (E)-3-alkylidene succinic anhydrides.

Hydroxamic acids

This invention provides a series of novel hydroxamic acids of formula I which are useful as inhibitors of metalloproteases such as endopeptidases.

Hydroxamic acids

The invention provides a series of novel hydroxamic acids of the formula I which are useful as inhibitors of metalloproteases such as endopeptidases and wherein R1 is a hydrophobic group, R2 and R3 are each an amino acid residue, n is 1 or 2, and A is a group of the formula:-, -CHR4.CO.NH2, in which R4 is an amino acid residue. Also described are processes for the manufacture of the hydroxamic acids, pharmaceutically acceptable salts derived from the said acids and pharmaceutical compositions containing a said acid or salt.

Stereospecific and Stereoselective Reactions. V. Alkylation of Active Methylene Compounds by the Use of Alcohols, Diethyl Azodicarboxylate, and Triphenylphosphine

The reagent formed by the reaction of diethyl azodicarboxylate (1) and triphenylphosphine (2) reacted with alcohols and ethyl cyanoacetate (6) to give alkylated products in 30 - 80percent yields.When ethyl acetoacetate, 1,3-1,3-coclopentanedione, or 1,3-cyclohexanedione was used in place of 6, the corresponding O-alkylated products were obtained.The reaction of either (S)-(-)-ethyl lactate or (S)-(-)-ethyl 2-hydroxy-3-phenylpropionate with 1, 2, and 6, followed by hydrolysis resulted in the formation of (S)-(-)-methylsuccinic acid or (S)-(-)-benzylsuccinic acid.The results indicate that nearly complete inversion of the configuration takes place in the alkylation step.