350-57-2

Basic information

• Product Name: (1,1,2,2-TETRAFLUOROETHOXY)BENZENE
• Synonyms: (1,1,2,2-Tetrafluoroethoxy)benzene, Phenyl 1,1,2,2-tetrafluoroethyl ether;alpha,alpha,beta,beta-Tetrafluorophenetole 98%;TETRAFLUOROETHOXYBENZENE;(1,1,2,2-tetrafluoroethoxy)-benzen;fentalene-14;(1,1,2,2-TETRAFLUOROETHOXY)BENZENE;TETRAFLUOROETHOXYBENZENE 98%;(1,1,2,2-Tetrafluoroethoxy)benzene98%
• CAS NO: 350-57-2
• Molecular Formula: C₈H₆F₄O
• Molecular Weight: 194.13
• EINECS: 206-505-4
• Product Categories: Oxygen Compounds;Ethers;Organic Building Blocks
• Mol File: 350-57-2.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 152-153 °C(lit.)
• Flash Point: 115 °F
• Appearance: /
• Density: 1.275 g/mL at 25 °C(lit.)
• Vapor Pressure: 4.07mmHg at 25°C
• Refractive Index: n20/D 1.4200(lit.)
• CAS DataBase Reference: (1,1,2,2-TETRAFLUOROETHOXY)BENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: (1,1,2,2-TETRAFLUOROETHOXY)BENZENE(350-57-2)
• EPA Substance Registry System: (1,1,2,2-TETRAFLUOROETHOXY)BENZENE(350-57-2)

Safety Data

• Hazard Codes: Xi,T
• Statements: 10-36/37/38
• Safety Statements: 26-36
• RIDADR: UN 1993 3/PG 3
• WGK Germany: 2
• RTECS: DC0340000
• HazardClass: TOXIC
• PackingGroup: III
• Hazardous Substances Data: 350-57-2(Hazardous Substances Data)

Usage

General Description

(1,1,2,2-Tetrafluoroethoxy)benzene, also known as FEB, is a chemical compound with the molecular formula C8H6F4O. It is a colorless liquid that is commonly used as a solvent in various industrial processes, including the production of polymers and electronics. FEB is highly stable and has a low volatility, making it a popular choice for applications that require a non-reactive and non-flammable solvent. It is also known for its excellent thermal and chemical stability, making it suitable for use in high-temperature and harsh chemical environments. Additionally, FEB is considered non-toxic and non-hazardous, further adding to its appeal for industrial use.

InChI:InChI=1/C8H6F4O/c9-7(10)8(11,12)13-6-4-2-1-3-5-6/h1-5,7H

Upstream product

• 116-14-3 polytetrafluoroethylene 
• 108-95-2 phenol 
• 124-73-2 1,2-dibromo-1,1,2,2-tetrafluoroethane 
• 100-67-4 potassium phenolate 
• 83015-28-5 1,1,2,2-tetrafluoro-1-bromo-2-phenoxyethane 

Downstream Products

• 1431266-14-6 sodium-4-(1,1,2,2-tetrafluorethoxy)benzenesulfonate 
• 772-53-2 (1,2,2-trifluorovinyloxy)benzene 
• 68516-54-1 4-(1,1,2,2-Tetrafluoroethoxy)benzenesulfonyl chloride 

Relevant articles and documents

A practical synthesis of aryl tetrafluoroethyl ethers via the improved reaction of phenols with 1,2-dibromotetrafluoroethane

An efficient and practical synthesis of various aryl tetrafluoroethyl ethers by the reaction of phenols with 1,2-dibromotetrafluoroethane and the subsequent reduction with zinc dust was described. The nucleophilic substitution of 1,2-dibromotetrafluoroethane with phenols initiated by bromophilic attack was improved by using Cs2CO3 as a base and DMSO as a solvent.

A mild hydrodehalogenation of fluoroalkyl halides

A mild hydrodehalogenation reaction of fluoroalkyl halides (RfCF2X, X = Br, I) has been developed under weakly basic conditions, giving the corresponding hydrogenolysis products with moderate to high yields.

SPONTANEOUS REACTIONS OF POTASSIUM PHENOXIDE WITH DIBROMOPERFLUOROALKANES. FIRST EVIDENCE FOR BROMOPHILIC ATTACK ON C-Br BONDS BY THE PHENOXIDE ION.

In contrast to earlier reports, It has been found that dibromoperfluoroalkanes actually can react spontaneously with PhOK, yielding fluoroalkyl phenyl ethers as products.Evidence for an anionic chain mechanism involving a bromophilic attack by the phenoxyde ion is presented.