34996-80-0Relevant articles and documents
A Convenient Synthesis of 3,4-Dihydroxyphenylalanine (DOPA)
Ali, Mohammed,Khan, Naseem H.
, p. 868 - 869 (2007/10/02)
A modified method for the synthesis of 3,4-dihydroxyphenylalanine (IV) is described.It involves catalytic (Raney Ni or 10percent Pd-C) hydrogenation of 4-(4'-acetoxy-3'-methoxybenzal)-2-phenyl-5-oxazolone (I) followed by hydrolysis of the reduced product N-Benzoyl-β-(4-hydroxy-3-methoxyphenyl)alaninamide (II) to give N-benzoyl-β-(4-hydroxy-3-methoxyphenyl)alanine (III) or IV in high yields under different conditions.