34730-78-4

Basic information

• Product Name: SCUTELLAREIN TETRAMETHYLETHER(RG)
• Synonyms: 3,4-Divanilyltetrahydrofuran;3,4-divanillyltetrahydrofura (Neetle Root extract);4,4'-[(Tetrahydro-3,4-furandiyl)bis(methylene)]bis[2-methoxyphenol];4,4'-(tetrahydrofuran-3,4-diyldiMethanediyl)bis(2-Methoxyphenol);3,4-divanillyltetrahydrofuran (Nettle root extract );4,4'-(Tetrahydrofuran-3,4-diyl)bis(methylene)bis(2-methoxyphenol)
• CAS NO: 34730-78-4
• Molecular Formula: C₂₀H₂₄O₅
• Molecular Weight: 344.40156
• Mol File: 34730-78-4.mol
• Article Data: 2

Chemical Properties

• Melting Point: 116-117℃
• Boiling Point: 527.8 °C at 760 mmHg
• Flash Point: 273 °C
• Appearance: /
• Density: 1.224
• PKA: 9.80±0.20(Predicted)
• CAS DataBase Reference: SCUTELLAREIN TETRAMETHYLETHER(RG)(CAS DataBase Reference)
• NIST Chemistry Reference: SCUTELLAREIN TETRAMETHYLETHER(RG)(34730-78-4)
• EPA Substance Registry System: SCUTELLAREIN TETRAMETHYLETHER(RG)(34730-78-4)

Safety Data

• Hazardous Substances Data: 34730-78-4(Hazardous Substances Data)

Usage

Description

SCUTELLAREIN TETRAMETHYLETHER (RG) is a bioactive chemical compound derived from the flavone scutellarein, which is found in medicinal plants such as Scutellaria baicalensis (Chinese skullcap) and the Dendrobium species (orchids). It possesses a range of potential pharmacological properties, including anti-inflammatory, antioxidant, and antimicrobial activities, making it a promising candidate for applications in medicine and pharmaceutics.

Uses

Used in Pharmaceutical Industry:
SCUTELLAREIN TETRAMETHYLETHER (RG) is used as a bioactive compound for its potential therapeutic applications due to its diverse pharmacological properties, such as anti-inflammatory, antioxidant, and antimicrobial activities.
Used in Medicinal Plants:
SCUTELLAREIN TETRAMETHYLETHER (RG) is used as a bioactive constituent in medicinal plants like Scutellaria baicalensis and Dendrobium species, contributing to their therapeutic effects.
Further research is needed to explore the specific biological effects and potential therapeutic uses of SCUTELLAREIN TETRAMETHYLETHER (RG) in various fields of medicine and pharmaceutics.

Upstream product

• 29388-59-8 (+/-)-secoisolariciresinol 
• 158932-33-3 secoisolariciresinol diglucoside 
• 2426-87-1 3-methoxy-4-(phenylmethoxy)benzaldehyde 
• 190004-70-7 dimethyl 2,3-bis-(4-hydroxy-3-methoxybenzyl)succinate 
• 96917-18-9 2,3-Bis-(4-benzyloxy-3-methoxy-benzyl)-succinic acid dimethyl ester 
• 96917-15-6 (E)-2-(4'-benzyloxy-3'-methoxybenzylidene)succinic acid 

Relevant articles and documents

A novel monitoring approach for mammalian lignan precursors in flaxseed

The mammalian lignans enterolactone and enterodiol have gained reputation as cancer-protective agents. These substances are produced in man by a gut microfloral-promoted transformation of opportune plant lignan precursors such as secoisolariciresinol diglucoside (3). This lignan is largely contained in flaxseed in the form of a more complex glucoside of still undisclosed structure and thus unsuitable for direct quantitative procedures. Since flaxseed-supplemented diets are usually employed to investigate the cancer-protective effect of a high mammalian lignan producing diet, a rapid and reliable analytical method for assaying 3 yield in flaxseed would be highly desirable. Acid hydrolysis of defatted flaxseed gives rise to 3,4-bis[(3-methoxy-4-hydroxy-phenyl)meth tetrahydrofuran (5), a degradation product readily amenable to gas chromatography resulting from the quantitative secoisolariciresinol-carrying complex glucoside cleavage. A gas chromatography-based internal standard method was then set up to derive the true content of 3 from the quantitative determination of the hydrolysis product 5. The method can reliably quantitate 5 with good linearity, accuracy and precision.