3433-56-5 Usage
Description
1-(1-phenylethenyl)pyrrolidine, also known as PEP, is a chemical compound with the formula C14H17N. It is a bicyclic amine characterized by its colorless liquid form, sweet, floral odor, and solubility in organic solvents. PEP is recognized for its utility as a chiral ligand in asymmetric catalysis and serves as a precursor in the synthesis of pharmaceutical drugs and other organic compounds. Due to its potentially hazardous nature, it is crucial to handle this compound with care.
Uses
Used in Asymmetric Catalysis:
1-(1-phenylethenyl)pyrrolidine is used as a chiral ligand for enhancing the selectivity and efficiency of asymmetric catalysis. Its unique structure allows for the creation of specific stereoisomers, which are essential in the production of various pharmaceuticals and fine chemicals.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, 1-(1-phenylethenyl)pyrrolidine is utilized as a precursor in the synthesis of a range of drugs and organic compounds. Its role in the development of new medications is significant, as it contributes to the creation of molecules with specific therapeutic properties.
Used in Organic Chemistry:
1-(1-phenylethenyl)pyrrolidine is also employed in organic chemistry as a versatile building block for the synthesis of complex organic molecules. Its bicyclic amine structure makes it a valuable component in the development of novel compounds with diverse applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 3433-56-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,4,3 and 3 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 3433-56:
(6*3)+(5*4)+(4*3)+(3*3)+(2*5)+(1*6)=75
75 % 10 = 5
So 3433-56-5 is a valid CAS Registry Number.
3433-56-5Relevant articles and documents
Visible light-induced intermolecular radical addition: Facile access to γ-ketoesters from alkyl-bromocarboxylates and enamines
Hu, Bei,Chen, Haixia,Liu, Yan,Dong, Wuheng,Ren, Kai,Xie, Xiaomin,Xu, Hao,Zhang, Zhaoguo
, p. 13547 - 13550 (2015/01/09)
A highly efficient addition of alkyl α-bromocarboxylates to enamines by visible light-induced photoredox catalysis is reported. Compared with traditional methods, the reaction described here provided an alternative route for the construction of valuable γ-ketoesters in generally good yields.
A new reactivity pattern for vinyl bromides: Cine-substitution via palladium catalysed C-N coupling/Michael addition reactions
Willis, Michael C.,Chauhan, Jay,Whittingham, William G.
, p. 3094 - 3095 (2007/10/03)
Palladium catalysed C-N bond formation can be used to convert vinyl bromides to the corresponding enamines, which are reacted in situ with alkylidene malonates to provide Michael adducts. The overall transformation results in cine-substitution of the starting vinyl bromide. The Royal Society of Chemistry 2005.