343255-27-6

Basic information

• Product Name: N,N-dimethyl-2-(4-{4-[4-(hydroxy-diphenylmethyl)-piperidin-1-yl]-butyryl}-phenyl)-isobutyramide
• Synonyms: N,N-dimethyl-2-(4-{4-[4-(hydroxy-diphenylmethyl)-piperidin-1-yl]-butyryl}-phenyl)-isobutyramide
• CAS NO: 343255-27-6
• Molecular Weight: 526.719
• Mol File: 343255-27-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N,N-dimethyl-2-(4-{4-[4-(hydroxy-diphenylmethyl)-piperidin-1-yl]-butyryl}-phenyl)-isobutyramide(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-dimethyl-2-(4-{4-[4-(hydroxy-diphenylmethyl)-piperidin-1-yl]-butyryl}-phenyl)-isobutyramide(343255-27-6)
• EPA Substance Registry System: N,N-dimethyl-2-(4-{4-[4-(hydroxy-diphenylmethyl)-piperidin-1-yl]-butyryl}-phenyl)-isobutyramide(343255-27-6)

Safety Data

• Hazardous Substances Data: 343255-27-6(Hazardous Substances Data)

Upstream product

• 169280-17-5 2-[4-(4-Chloro-butyryl)-phenyl]-2-methyl-propionic acid , dimethylamide 
• 115-46-8 C₁₈H₂₁NO 

Downstream Products

• 169280-28-8 N,N-dimethyl-2-(4-{1-hydroxy-4-[4-(hydroxy-diphenylmethyl)-piperidin-1-yl]-butyry}-phenyl)-isobutyramide 

Relevant articles and documents

Intermediates useful for the preparation of antihistaminic piperidine derivatives

The present invention is related to a novel intermediates and processes which are useful in the preparation of certain antihistaminic piperidine derivatives of the formula whereinW represents —C(=O)— or —CH(OH)—;R1 represents hydrogen or hydroxy;R2 represents hydrogen;R1 and R2 taken together form a second bond between the carbon atoms bearing R1 and R2;n is an integer of from 1 to 5;m is an integer 0 or 1;R3 is —COOH or —COOalkyl wherein the alkyl moiety has from 1 to 6 carbon atoms and is straight or branched each of A is hydrogen or hydroxy; and pharmaceutically acceptable salts and individual optical isomers thereof,with the proviso that where R1 and R2 are taken together to form a second bond between the carbon atoms bearing R1 and R2 or where R1 represented hydroxy, m is an integer 0.