338945-22-5 Usage
Description
(S)-2-IodoMethyl-pyrrolidine-1-carboxylic acid tert-butyl ester is a chemical compound with the molecular formula C10H18INO2. It is a tert-butyl ester derivative of pyrrolidine-1-carboxylic acid that contains an iodoMethyl group on the second position of the pyrrolidine ring. This chiral compound, known for its different optical properties as an enantiomer, is a valuable building block in organic synthesis and medicinal chemistry, particularly for the development of pharmaceutical drugs.
Uses
Used in Organic Synthesis:
(S)-2-IodoMethyl-pyrrolidine-1-carboxylic acid tert-butyl ester is used as a key intermediate for the synthesis of various bioactive molecules. Its unique structure and functional groups allow for further chemical modifications, making it a versatile component in creating a wide range of compounds with potential applications.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (S)-2-IodoMethyl-pyrrolidine-1-carboxylic acid tert-butyl ester is used as a starting material for the development of pharmaceutical drugs. Its chiral nature and chemical properties make it an attractive candidate for designing and synthesizing novel drug molecules with improved efficacy and selectivity.
Used in Pharmaceutical Drug Development:
(S)-2-IodoMethyl-pyrrolidine-1-carboxylic acid tert-butyl ester is utilized as a crucial building block in the creation of new pharmaceutical compounds. Its potential applications in this industry stem from its ability to be incorporated into various drug molecules, contributing to the development of innovative treatments for a range of medical conditions.
Used in Chiral Compound Research:
(S)-2-IodoMethyl-pyrrolidine-1-carboxylic acid tert-butyl ester is also used in the study of chiral compounds, which are essential in understanding the differences in biological activity and pharmacological effects between enantiomers. This research can lead to the development of more effective and safer drugs by exploiting the unique properties of chiral molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 338945-22-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,3,8,9,4 and 5 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 338945-22:
(8*3)+(7*3)+(6*8)+(5*9)+(4*4)+(3*5)+(2*2)+(1*2)=175
175 % 10 = 5
So 338945-22-5 is a valid CAS Registry Number.
338945-22-5Relevant articles and documents
A Bifunctional B,N-Based Asymmetric Catalytic Nitrostyrene-Michael Addition Acting through a 10-Membered Ring Cyclic Transition State
Du, Yihao,Erdem, Safiye S.,Sari, Ozlem,Whiting, Andrew
, (2021/11/17)
The B,N-bifunctional catalyst homoboroproline has been applied to a catalytic asymmetric nitroalkene-Michael addition to β-nitrostyrene analogues, showing broad substrate tolerance, high conversions and moderate to good asymmetric induction. The ability o
Sequential deprotectionecyclisation reaction: Stereoselective synthesis of azabicyclic β-enamino ester derivatives and (-) indolizidine 209D
Ponpandian, Thanasekaran,Muthusubramanian, Shanmugam
, p. 527 - 536 (2013/07/27)
This paper describes a new strategy for the stereoselective synthesis of pyrrolizidine and indolizidine based enamino esters and their acyl derivatives from L-proline. The key reaction in this process involves deprotection followed by ring closure of cyclic N-Boc amino-β-ketoesters. Also, the synthesis of 5R,9R- (-)-indolizidine 209D has been accomplished using this protocol.
The diastereoselective alkylation of arenesulfenate anions using homochiral electrophiles
Soederman, Stefan C.,Schwan, Adrian L.
supporting information; experimental part, p. 4192 - 4195 (2011/10/08)
A series of Boc-protected β-amino sulfoxides were prepared by the reaction of arenesulfenate anions with chiral Boc-protected β-amino iodides. The stereoselective substitution reaction is believed to arise through precoordination of the sulfenate counteri