33884-43-4 Usage
Description
2-(2-Bromoethyl)-1,3-dioxane is an organic compound that features a 1,3-dioxane ring with a bromoethyl group attached to the second carbon. This structure endows it with unique chemical properties, making it a versatile intermediate in organic synthesis.
Uses
Used in Pharmaceutical Synthesis:
2-(2-Bromoethyl)-1,3-dioxane is used as a synthetic intermediate for the preparation of complex organic molecules, particularly in the pharmaceutical industry. Its unique structure allows for the creation of various medicinal compounds with potential therapeutic applications.
Used in Organic Chemistry Research:
In the field of organic chemistry, 2-(2-Bromoethyl)-1,3-dioxane serves as a valuable building block for the synthesis of novel compounds. Its reactivity and structural features make it an ideal candidate for exploring new chemical reactions and developing innovative synthetic pathways.
Specifically, 2-(2-Bromoethyl)-1,3-dioxane has been utilized in the synthesis of ketone adducts such as 2-[3-oxo-4(S)-(triphenylmethyl)amino-6-methylheptyl]-1,3-dioxane and 2-[3-oxo-4(S)-(triphenylmethyl)amino-6-methylheptyl]-1,3-dioxolane. These adducts are of interest due to their potential applications in medicinal chemistry and drug development.
Check Digit Verification of cas no
The CAS Registry Mumber 33884-43-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,3,8,8 and 4 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 33884-43:
(7*3)+(6*3)+(5*8)+(4*8)+(3*4)+(2*4)+(1*3)=134
134 % 10 = 4
So 33884-43-4 is a valid CAS Registry Number.
InChI:InChI=1/C6H11BrO2/c1-5(7)6-8-3-2-4-9-6/h5-6H,2-4H2,1H3
33884-43-4Relevant articles and documents
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Stowell,J.C.
, p. 560 - 561 (1976)
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Preparation and properties of a novel solution of hydrogen bromide (HBr) in 1,4-dioxane: An alternative reagent to HBr gas without protic solvents
Nishio, Yuya,Mifune, Ryota,Sato, Taisuke,Ishikawa, Shin-ich,Matsubara, Hiroshi
, p. 1190 - 1193 (2017/03/02)
A solution of hydrogen bromide (HBr) in 1,4-dioxane was prepared and investigated for its ability to brominate alcohols, and hydrobrominate alkenes. This study revealed that the brominating ability of this HBr/1,4-dioxane solution is equal or superior to that of hydrobromic acid or HBr in acetic acid. The solution of HBr in 1,4-dioxane is robust, exhibiting no decomposition of the solvent, and retaining 97% of its original concentration, when kept at ?25 °C for 30 days. This solution is a liquid alternative to HBr gas without protic solvents.
AN ECONOMICAL PREPARATION OF 2-(2-BROMOETHYL)-1,3-DIOXANE
Christensen, Jorn B.,Schluter, Anne
, p. 355 - 357 (2007/10/02)
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