33816-51-2 Usage
Description
5-BROMO-2-METHOXYCYCLOHEPTA-2,4,6-TRIEN-1-ONE is a chemical compound characterized by the molecular formula C8H9BrO2. It is a substituted cyclohepta-trienone with a bromine atom at the 5-position and a methoxy group at the 2-position, which endows it with unique structural and reactivity features. 5-BROMO-2-METHOXYCYCLOHEPTA-2,4,6-TRIEN-1-ONE is recognized for its potential in various applications, particularly in the synthesis of pharmaceuticals and agrochemicals, as well as in medicinal chemistry research due to its distinctive properties.
Uses
Used in Organic Synthesis:
5-BROMO-2-METHOXYCYCLOHEPTA-2,4,6-TRIEN-1-ONE is utilized as a key intermediate in organic synthesis, serving as a building block for the creation of a variety of complex organic molecules. Its unique structure allows for versatile chemical reactions, making it a valuable component in the synthesis of new compounds.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 5-BROMO-2-METHOXYCYCLOHEPTA-2,4,6-TRIEN-1-ONE is used as a precursor for the preparation of various pharmaceuticals. Its reactivity and structural features make it suitable for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
5-BROMO-2-METHOXYCYCLOHEPTA-2,4,6-TRIEN-1-ONE also finds application in the agrochemical industry, where it is used in the synthesis of compounds with pesticidal properties. Its potential to be incorporated into effective agrochemicals contributes to its importance in this field.
Used in Medicinal Chemistry Research:
Due to its unique structure and reactivity, 5-BROMO-2-METHOXYCYCLOHEPTA-2,4,6-TRIEN-1-ONE is studied for its potential biological activities and pharmacological properties in medicinal chemistry. Researchers explore its interactions with biological targets to discover new therapeutic agents or understand its mechanisms of action.
While the provided materials do not specify distinct applications in different industries beyond the general uses in organic synthesis, pharmaceuticals, and agrochemicals, and its role in medicinal chemistry research, the compound's versatility suggests that it may have additional applications that are yet to be fully explored or documented.
Check Digit Verification of cas no
The CAS Registry Mumber 33816-51-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,3,8,1 and 6 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 33816-51:
(7*3)+(6*3)+(5*8)+(4*1)+(3*6)+(2*5)+(1*1)=112
112 % 10 = 2
So 33816-51-2 is a valid CAS Registry Number.
InChI:InChI=1/C8H7BrO2/c1-11-8-5-3-6(9)2-4-7(8)10/h2-5H,1H3
33816-51-2Relevant articles and documents
TROPOLONE DERIVATIVES AND TAUTOMERS THEREOF FOR IRON REGULATION IN ANIMALS
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Page/Page column 197; 198, (2021/04/23)
Disclosed are a series of compounds or their tautomers having a general structure represented by Formula (la), (lb), (Ila), (lIb), or (lIc) and pharmaceutically acceptable salts thereof. The present disclosure also relates to pharmaceutical compositions comprising said compounds or tautomers. The present disclosure further relates to a method of treating a disease or condition associated with iron dysregulation or dysfunctional iron homeostasis comprising administering to a subject in need thereof a therapeutically effective amount of Formula (la), (lb), (Ila), (lIb), or (lIc) compounds or tautomers.
Efforts directed toward the synthesis of colchicine: Application of palladium-catalyzed siloxane cross-coupling methodology
Seganish, W. Michael,Handy, Christopher J.,DeShong, Philip
, p. 8948 - 8955 (2007/10/03)
Colchicine is an important and synthetically challenging natural product. The key synthetic step in this approach to the synthesis of colchicine involved a palladium-catalyzed cross-coupling reaction between 5-bromotropolone (4) and an aryl siloxane to form the aryl-tropolone bond. The coupling of a variety of highly functionalized aryl siloxane derivatives was investigated and optimized coupling conditions were developed. It was discovered that a palladium catalyst with a high degree of phosphine ligand coordination (5 equiv of phosphine/mol Pd) was necessary to efficiently couple aryl siloxanes with 5-bromotropolone (4). In addition, the coupling approach has provided a direct comparison between siloxane and boronic acid coupling technologies that demonstrated that aryl siloxanes and boronic acids produce similar yields of highly functionalized biaryl products.
Syntheses and ipso-substitution reactions of some C-stannylated troponoids
Banwell, Martin G.,Cameron, Jennifer M.,Collis, Maree P.,Gravatt, G. Lance
, p. 395 - 407 (2007/10/03)
The C-stannylated troponoids (2)-(8) have been prepared and two of these shown to undergo palladium(0)-catalysed cross-coupling with bromobenzene to give the corresponding phenyl-substituted tropone. Compounds (3), (5) and (6)-(8) all react with electrophiles to give products of ipso-substitution.
