33620-66-5

Basic information

• Product Name: 1,3-Benzenediol, 5-[2-(4-methoxyphenyl)ethenyl]-, diacetate, (E)-
• CAS NO: 33620-66-5
• Molecular Formula: C19H18O5
• Molecular Weight: 326.349
• Mol File: 33620-66-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1,3-Benzenediol, 5-[2-(4-methoxyphenyl)ethenyl]-, diacetate, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Benzenediol, 5-[2-(4-methoxyphenyl)ethenyl]-, diacetate, (E)-(33620-66-5)
• EPA Substance Registry System: 1,3-Benzenediol, 5-[2-(4-methoxyphenyl)ethenyl]-, diacetate, (E)-(33620-66-5)

Safety Data

• Hazardous Substances Data: 33620-66-5(Hazardous Substances Data)

Upstream product

• 65728-21-4 5-[(E)-2-(4-methoxyphenyl)vinyl]benzene-1,3-diol 
• 108-24-7 acetic anhydride 
• 637-69-4 4-Methoxystyrene 
• 39192-49-9 3,5-diacetoxybenzoyl chloride 
• 123-11-5 4-methoxy-benzaldehyde 
• 29680-76-0 3,5-diacetoxybenzyl-(triphenyl)phosphonium bromide 
• 504-15-4 orcinol 
• 104311-39-9 5-(bromomethyl)-1,3-phenylene diacetate 
• 20982-28-9 5-methylbenzene-1,3-diyl diacetate 

Downstream Products

• 65728-21-4 5-[(E)-2-(4-methoxyphenyl)vinyl]benzene-1,3-diol 
• 110993-16-3 Acetic acid 3-acetoxy-5-[2-(4-methoxy-phenyl)-ethyl]-phenyl ester 
• 90332-29-9 α,β-dihydro-3,5-dihydroxy-4'-methoxystilbene 
• 110993-17-4 dimethoxycarbonyloxy-3',5' methoxy-4'' diphenyl-1,2 ethane 

Relevant articles and documents

Synthesis of resveratrol derivatives as new analgesic drugs through desensitization of the TRPA1 receptor

A series of 31 resveratrol derivatives was designed, synthesized and evaluated for activation and inhibition of the TRPA1 channel. Most acted as activators and desensitizers of TRPA1 channels like resveratrol or allyl isothiocyanate (AITC). Compound 4z (HUHS029) exhibited higher inhibitory activity than resveratrol with an IC50 value of 16.1?μM. The activity of 4z on TRPA1 was confirmed in TRPA1-expressing HEK293 cells, as well as in rat dorsal root ganglia neurons by a whole cell patch clamp recording. Furthermore, pretreatment with 4z exhibited an analgesic effect on AITC-evoked TRPA1-related pain behavior in vivo.

Spasmolytic Principle from Rheum webbianum Royle

The structure of spasmolytic principle, isolated from Rheum webbianum, has ben established as 3',5'-dihydroxy-4-methoxystilbene on the basis of physico-chemical studies.