33155-60-1

Basic information

• Product Name: METHYL 4-TERT-BUTYLPHENYLACETATE, 97
• Synonyms: METHYL 4-TERT-BUTYLPHENYLACETATE, 97;Methyl 4-t-Butylphenylacetate;tert-Butyl 4-methylbenzeneacetate;tert-Butyl p-tolylacetate
• CAS NO: 33155-60-1
• Molecular Formula: C₁₃H₁₈O₂
• Molecular Weight: 206.28
• EINECS: 222-602-4
• Mol File: 33155-60-1.mol
• Article Data: 17

Chemical Properties

• Boiling Point: 149-151°C 30mm
• Flash Point: >100°C
• Appearance: /
• Density: 0,994 g/cm3
• Vapor Pressure: 0.00778mmHg at 25°C
• Refractive Index: 1.491
• CAS DataBase Reference: METHYL 4-TERT-BUTYLPHENYLACETATE, 97(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 4-TERT-BUTYLPHENYLACETATE, 97(33155-60-1)
• EPA Substance Registry System: METHYL 4-TERT-BUTYLPHENYLACETATE, 97(33155-60-1)

Safety Data

• Safety Statements: S24/25:Avoid contact with skin and eyes.
• Hazardous Substances Data: 33155-60-1(Hazardous Substances Data)

Usage

Description

METHYL 4-TERT-BUTYLPHENYLACETATE, 97 is a chemical compound with a purity of 97%, characterized by its colorless liquid form and a sweet, citrus-like odor. It is renowned for its strong and long-lasting scent, making it a valuable ingredient in the creation of various fragrances and flavorings.
Used in Perfumery Industry:
METHYL 4-TERT-BUTYLPHENYLACETATE, 97 is used as a flavoring agent and fragrance ingredient for its pleasant aroma, enhancing the scent profiles of perfumes, soaps, and other scented products.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, METHYL 4-TERT-BUTYLPHENYLACETATE, 97 serves as a masking agent for bitter-tasting drugs, improving the palatability of medications and ensuring a better patient experience during consumption.
Used in Consumer Product Industry:
This chemical compound is also utilized in the production of various consumer products to provide a long-lasting and strong scent, contributing to the overall appeal and sensory experience of these goods.

InChI:InChI=1/C13H18O2/c1-13(2,3)11-7-5-10(6-8-11)9-12(14)15-4/h5-8H,9H2,1-4H3

Upstream product

• 106-38-7 para-bromotoluene 
• 762-75-4 tert-butyl formate 
• 201230-82-2 carbon monoxide 
• 104-81-4 4-Methylbenzyl bromide 
• 4498-99-1 4-methylbenzylthiol 
• 75-65-0 tert-butyl alcohol 
• 540-88-5 acetic acid tert-butyl ester 
• 622-47-9 4-tolylacetic acid 
• 36805-97-7 N,N-dimethylformamide di-tert-butyl acetal 
• 106-43-4 para-chlorotoluene 
• 5292-43-3 bromoacetic acid tert-butyl ester 
• 4294-57-9 para-methylphenylmagnesium bromide 
• 23786-13-2 methyl p-tolylacetate 
• 1907-33-1 lithium tert-butoxide 

Downstream Products

• 77292-91-2 α-(4-bromomethylphenyl)acetic acid tert-butyl ester 
• 222842-90-2 4-(tert-butoxycarbonylmethyl)-L-phenylalanine 
• 222843-51-8 benzyl (2R,3S)-3-<4-(tert-butoxycarbonylmethyl)phenyl>-2-oxo-5,6-diphenyl-morpholine-4-carboxylate 
• 85278-61-1 (E)-3-Fluoro-2-p-tolyl-prop-2-en-1-ol 
• 850088-53-8 (E)-3-Fluoro-2-p-tolyl-acrylic acid ethyl ester 
• 85278-64-4 (E)-3-Fluoro-2-p-tolyl-allylamine; hydrochloride 
• 127152-94-7 (+/-)-α-(acetylamino)-4-<2-(1,1-dimethylethoxy)-2-oxoethyl>benzenepropanoic acid 
• 127152-88-9 (+/-)-α-(acetylamino)-4-<2-(1,1-dimethylethoxy)-2-oxoethyl>benzenepropanoic acid phenylmethyl ester 
• 127152-70-9 (+/-)-4-<(1,1-dimethylethoxy)-2-oxoethyl>-α-<(diphenylmethylene)amino>benzenepropanoic acid phenylmethyl ester 
• 127152-79-8 (+/-)-4-<2-(1,1-dimethylethoxy)-2-oxoethyl>-α-aminobenzenepropanoic acid phenylmethyl ester p-toluenesulfonate 
• 157312-15-7 tert-butyl cyclopentyl(4-methylphenyl)acetate 
• 1005415-66-6 tert-butyl 2-diazo-2-(4-methylphenyl)acetate 
• 1150277-39-6 tert-butyl (1-[chloro(p-tolylsulfinyl)methyl]cyclobutyl)-p-tolylacetate 
• 1197333-07-5 C₂₂H₃₀O₄ 

Relevant articles and documents

Erratum: Oxazaborolidinium Ion-Catalyzed Cyclopropanation of α-Substituted Acroleins: Enantioselective Synthesis of Cyclopropanes Bearing Two Chiral Quaternary Centers (J. Am. Chem. Soc. (2011) 133:51 (20708?20711) DOI: 10.1021/ja209270e)

Pages 20709 and 20710. In the published version of the paper, the trans:cis ratios of 2w and 2x were reversed. The revised results were confirmed by NOE experiments and comparison of the optical rotation data with reported values after transformation. The

Catalytic Asymmetric Darzens-Type Epoxidation of Diazoesters: Highly Enantioselective Synthesis of Trisubstituted Epoxides

Highly enantioselective Darzens-type epoxidation of diazoesters with glyoxal derivatives was accomplished using a chiral boron–Lewis acid catalyst, which facilitated asymmetric synthesis of trisubstituted α,β-epoxy esters. In the presence of a chiral oxazaborolidinium ion catalyst, the reaction proceeded in high yield (up to 99 %) with excellent enantio- and diastereoselectivity (up to >99 % ee and >20:1 dr, respectively). The synthetic potential of this method was illustrated by conversion of the products to various compounds such as epoxy γ-butyrolactone, tertiary β-hydroxy ketone and epoxy diester.

Cu(I)/chiral bisoxazoline-catalyzed enantioselective sommelet-hauser rearrangement of sulfonium ylides

Catalytic asymmetric thia-Sommelet-Hauser rearrangement of sulfonium ylides remains a great challenge due to its multistep reaction mechanism involving metal carbene formation, proton transfer, and [2,3]-sigmatropic rearrangement. In particular, the key problem of such reactions is the differentiation of the enantiotopic lone pair electrons of sulfur, which generates the sulfonium ylide intermediate bearing chirality on the sulfur atom. With a modified chiral bisoxazoline ligand, we developed a Cu(I)- catalyzed asymmetric thia-Sommelet-Hauser rearrangement with good to excellent enantioselectivities. Mechanistic studies provide insights into the details of the reaction mechanism.