3296-90-0Relevant articles and documents
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Zelinski
, (1913)
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Mimicking biological membranes with programmable glycan ligands self-assembled from amphiphilic Janus glycodendrimers
Zhang, Shaodong,Moussodia, Ralph-Olivier,Sun, Hao-Jan,Leowanawat, Pawaret,Muncan, Adam,Nusbaum, Christopher D.,Chelling, Kathleen M.,Heiney, Paul A.,Klein, Michael L.,André, Sabine,Roy, René,Gabius, Hans-J.,Percec, Virgil
supporting information, p. 10899 - 10903 (2015/03/30)
An accelerated modular synthesis produced 18 amphiphilic Janus glycodendrimers with three different topologies formed from either two or one carbohydrate head groups or a mixed constellation with a noncarbohydrate hydrophilic arm. By simple injection of their THF solutions into water or buffer, all of the Janus compounds self-assembled into uniform, stable, and soft unilamellar vesicles, denoted glycodendrimersomes. The mixed constellation topology glycodendrimersomes were demonstrated to be most efficient in binding plant, bacterial, and human lectins. This evidence with biomedically relevant receptors offers a promising perspective for the application of such glycodendrimersomes in targeted drug delivery, vaccines, and other areas of nanomedicine.
Host-guest complexes of cucurbit[8]uril with some pentaerythritol derivative guests
Li, Xian-Mei,Fan, Fan,Lu, Jing-Song,Xue, Sai-Feng,Zhang, Yun-Qian,Zhu, Qian-Jiang,Tao, Zhu,Lawrance, Geofferey A.,Wei, Gang
scheme or table, p. 1088 - 1095 (2011/07/08)
A series of first generation dendritic guests from pentaerythritol derivatives have been designed and synthesized. Investigation of the complex structures of cucurbit[8]uril (Q[8]) and the guests based on the 1H NMR technique have revealed that the host Q[8] selectively included different branch(es) of the first generation dendritic guests and formed inclusion complexes with different structural conformations. The experimental results obtained from electronic absorption spectroscopy showed that the 1:1 ratio of Q[8]-based host-guest inclusion complexes have moderate stability with an average formation constants of 104 L mol-1. The single crystal structures of some of the guests (g5 and g6) and Q[8]-guest complexes (Q[8]-g4 and Q[8]-g6) further confirm but in some cases contradict the research results of the 1H NMR technique and electronic absorption spectroscopy in aqueous solution. The Royal Society of Chemistry and the Centre National de la Recherche Scientifique 2011.