32888-88-3

Basic information

• Product Name: 2-AMINO-5-CHLORO-1,4-BENZENEDICARBOXYLIC ACID
• Synonyms: 2-AMINO-5-CHLORO-TEREPHTHALIC ACID;2-AMINO-5-CHLORO-1,4-BENZENEDICARBOXYLIC ACID;2-aMino-5-chlorobenzene-1,4-dicarboxylic acid
• CAS NO: 32888-88-3
• Molecular Formula: C₈H₆ClNO₄
• Molecular Weight: 215.59
• Mol File: 32888-88-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 458 °C at 760 mmHg
• Flash Point: 230.8 °C
• Appearance: /
• Density: 1.674 g/cm³
• Vapor Pressure: 3.5E-09mmHg at 25°C
• Refractive Index: 1.69
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-AMINO-5-CHLORO-1,4-BENZENEDICARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-5-CHLORO-1,4-BENZENEDICARBOXYLIC ACID(32888-88-3)
• EPA Substance Registry System: 2-AMINO-5-CHLORO-1,4-BENZENEDICARBOXYLIC ACID(32888-88-3)

Safety Data

• Hazardous Substances Data: 32888-88-3(Hazardous Substances Data)

Usage

Description

2-AMINO-5-CHLORO-1,4-BENZENEDICARBOXYLIC ACID, also known as 5-Chlorophthaloyl Glycine, is a chemical compound characterized by the presence of an amino group and a chlorine atom on a benzene ring, which is further functionalized with two carboxylic acid groups. This unique structure endows it with versatile properties, making it a valuable building block in the synthesis of pharmaceuticals and agrochemicals.

Uses

Used in Pharmaceutical Industry:
2-AMINO-5-CHLORO-1,4-BENZENEDICARBOXYLIC ACID is used as a precursor in the manufacturing of various pharmaceuticals for its potential applications in medicine. Its unique chemical structure allows for the development of specialized drugs that can target specific biological pathways or diseases.
Used in Agrochemical Industry:
2-AMINO-5-CHLORO-1,4-BENZENEDICARBOXYLIC ACID is used as a building block in the synthesis of agrochemicals, contributing to the development of effective pesticides, herbicides, and other agricultural products.
Used in Polymer and Material Science:
2-AMINO-5-CHLORO-1,4-BENZENEDICARBOXYLIC ACID is used as a monomer or building block in the creation of specialized polymers and materials due to its unique chemical structure, which can impart specific properties to the resulting materials.
Safety Precautions:
It is important to handle 2-AMINO-5-CHLORO-1,4-BENZENEDICARBOXYLIC ACID with care, as it can be toxic if ingested or inhaled and can cause skin and eye irritation. Proper safety measures, such as wearing protective gear and working in a well-ventilated area, should be taken during its use and handling.

InChI:InChI=1/C8H6ClNO4/c9-5-1-4(8(13)14)6(10)2-3(5)7(11)12/h1-2H,10H2,(H,11,12)(H,13,14)

Upstream product

• 5372-81-6 dimethyl aminoterephthalate 
• 32888-87-2 2-amino-5-chloro-terephthalic acid dimethyl ester 

Downstream Products

• 32888-87-2 2-amino-5-chloro-terephthalic acid dimethyl ester 

Relevant articles and documents

Effect of the Metal within Regioisomeric Paddle-Wheel-Type Metal–Organic Frameworks

The effect of metal on the degree of flexibility upon evacuation of metal–organic frameworks (MOFs) has been revealed with positional control of the organic functionalities. Although Co-, Cu-, and Zn-based DMOFs (DMOF = DABCO MOF, DABCO = 1,4-diazabicyclo

PROLYL HYDROXYLASE INHIBITORS

The invention described herein relates to certain 2,4-dioxo-l,2,3,4-tetrahydro-7- quinazolinecarboxamide derivatives of formula (I) which are antagonists of HIF prolyl hydroxylases and are useful for treating diseases benefiting from the inhibition of this enzyme, anemia being one example.