326913-77-3Relevant articles and documents
Newer substituted β-aminonaphthalenes as potent anti-inflammatory agents
Bansal,Srivastava,Kumar
, p. 1009 - 1014 (2007/10/03)
β-[2-(3'-Chloro-2'-oxo-4'-substituted aryl-1'-azetidinyl)-thiazol-4-yl]aminonaphthalenes 13-17 and β-[2-(1',3'-disubstitutedphenyl-formazan-4'-yl)-thiazol-4-yl] aminonaphthalenes 8-12 were synthesized from β-(2-arylideneamino-thiazol-4-yl)aminonaphthalenes 3-7 by diazotisation and by cycloaddition with monochloroacetyl chloride, respectively, on the azomethine group of the compounds 3-7. The newly synthesized compounds showed potent anti-inflammatory and analgesic activities and were less ulcerogenic than phenylbutazone.