3237-34-1Relevant articles and documents
Solid-state deuterium NMR studies of organic molecules in the tectosilicate nonasil
Shantz, Daniel F.,Lobo, Raul F.
, p. 2339 - 2349 (1998)
Solid-state deuterium NMR spectroscopy is used to study the dynamics of organic molecules occluded in the as-synthesized high-silica tectosilicate nonasil. The nonasil samples are synthesized using trimethylalkyl-ammonium structure-directing agents to det
Influence of positively-charged guests on the superoxide dismutase mimetic activity of copper(II) β-cyclodextrin dithiocarbamates
Fragoso, Alex,Cao, Roberta,D'Souza, Valerian T.
, p. 171 - 180 (1997)
The superoxide dismutase (SOD) activity of the Cu(II) complexes of two dithiocarbamate derivatives of cyclodextrin (Cu-C6DTC, Cu-C2DTC), one on the primary (C6DTC) and the other on the secondary (C2DTC) side, was determined in the presence of positively-c
A Microscopic Hydrophobicity Parameter
Menger, F. M.,Venkataram, U. V.
, p. 2980 - 2984 (2007/10/02)
p-Nitrophenyl laurate at 1x1E-5 M in water forms aggregates within which the ester groups hydrolyze slowly (about 1E3 less than a short-chain monomer).Salts of the general structure RNMe3+X- disrupt or destroy the aggregates; the ester groups are thereby "deshielded", and the observed hydrolysis rate increases.The magnitude of the rate increase at a given salt concentration depends on R: the more hydrophobic the R group, the greater the rate enhancement.This observation provided the basis of a "microscopic" hydrophobicity parameter MH which was evaluated for 25 different Rs (e.g., MH=0.73, 0.97, and 1.33 for R=ethyl, n-butyl, and n-hexyl).MH values were used to assess the role of branching, unsaturation, cyclization, aromaticity, halogenation, etc., in hydrophobic association.The parameters correlate well with Hansch ? values for aliphatic substituents but not for aromatic groups.Since the MH scale is based on the specific binding of one molecule to another, it may be well suited for modeling association among bioactive species.
