3237-31-8

Basic information

• Product Name: NSC30185
• Synonyms: NSC30185
• CAS NO: 3237-31-8
• Molecular Formula: C₁₂H₁₇NO₂S
• Molecular Weight: 239.33388
• Mol File: 3237-31-8.mol
• Article Data: 28

Chemical Properties

• Boiling Point: 374.7°Cat760mmHg
• Flash Point: 180.4°C
• Appearance: /
• Density: 1.2g/cm³
• Vapor Pressure: 8.22E-06mmHg at 25°C
• Refractive Index: 1.569
• CAS DataBase Reference: NSC30185(CAS DataBase Reference)
• NIST Chemistry Reference: NSC30185(3237-31-8)
• EPA Substance Registry System: NSC30185(3237-31-8)

Safety Data

• Hazardous Substances Data: 3237-31-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H17NO2S/c14-16(15,12-9-5-2-6-10-12)13-11-7-3-1-4-8-11/h2,5-6,9-11,13H,1,3-4,7-8H2

Upstream product

• 108-91-8 cyclohexylamine 
• 98-09-9 benzenesulfonyl chloride 
• 155164-57-1 2-benzenesulfonyl-4,5-dichloropyridazin-3-one 
• 98-10-2 benzenesulfonamide 
• 110-83-8 cyclohexene 
• 98-11-3 benzenesulfonic acid 
• 35810-04-9 benzenesulfinic acid cyclohexylamide 
• 54769-59-4 N-hydroxybenzotriazole ester of benzenesulfonic acid 
• 108-94-1 cyclohexanone 
• 873-55-2 sodium benzenesulfonate 
• 110-82-7 cyclohexane 
• 80-17-1 benzenesufonyl hydrazide 
• 108-98-5 thiophenol 
• 603-33-8 triphenylbismuthane 

Downstream Products

• 200408-41-9 2,2'-diselenobis(N-cyclohexyl benzenesulfonamide) 
• 1620220-80-5 C₁₆H₂₁NO₃S 
• 1620220-90-7 1-cyclohexyl-3-methyl-3-(tosylmethyl)indolin-2-one 
• 41595-23-7 N-Cyclohexyl-N-(benzolsulfenyl)benzolsulfonamid 
• 15963-66-3 N-Chlor-N-benzolsulfonyl-cyclohexylamin 
• 65299-65-2 N-Cyclohexyl-N,N-di(benzol)sulfonimid 

Relevant articles and documents

AEROBIC OXIDATIVE SYNTHESIS OF SULFONAMIDE USING Cu CATALYST

The present invention relates to a method for oxidative synthesis of sulfonamides using copper catalysts. , Oxygen (O) is used. 2 The oxidative synthesis of sulfonamides (1) comprises reacting a 2 th or sulfonyl hydrazide primary amine with a sulfonyl hydrazide (sulfonamide) with a copper catalyst on a solvent under the conditions in which the sulphonamide is fed. The oxidation coupling of the present invention showed extensive substrate ranges in an amine comprising a 2 primary amine, 1 primary amine and amine hydrochloride salt. It is worth notable that non-reactive aliphatic sulfonyl hydrazides in previously reported anaerobic systems can be used for the aerobic oxidation coupling of the present invention. The oxidation coupling of the present invention has been more effective on large scale.

A Versatile Electrochemical Batch Reactor for Synthetic Organic and Inorganic Transformations and Analytical Electrochemistry

A standardized and versatile electrochemical batch reactor that has wide applicability in both organic and inorganic synthesis and analytical electrochemistry has been developed. A variety of synthetic electrochemical transformations have been performed to showcase the versatility and demonstrate the reactor, including the synthesis of five Cu(I)-NHC complexes, two Au(I)-NHC complexes, and one Fe(II)-NHC complex as well as an Fe(III)-salen complex. The reactor is based on a commercially available vial with an adapted lid, making it inexpensive and highly flexible. It features a fixed interelectrode distance, which is crucial for reproducibility, along with the ability to accommodate a variety of interchangeable electrode materials. The reactor has also been used in conjunction with a parallel plate, allowing rapid screening and optimization of an organic electrochemical transformation. Cyclic voltammetry has been performed within the reactor on a range of imidazolium salt analytes with the use of an external potentiostat. The ability to use this reactor for both analytical and synthetic organic and inorganic chemistry is enabled by a flexible and characterizable design.

Hypervalent Iodine Mediated Sulfonamide Synthesis

A new metal-free sulfonylation reaction is described. The method takes advantage of the Umpolung reactivity and group-transfer properties of iodine(III) compounds, combining hypervalent iodine reagents and sulfinate salts to deliver a clean and mild transfer of sulfonyl groups to amines and anilines. A total of 25 sulfonamides was synthesised in up to 99 % yield, even on gram-scale. The reaction mechanism was investigated by ESI-MS and DFT calculations.