32065-66-0

Basic information

• Product Name: 2-(dimethoxymethyl)quinoxaline 1,4-dioxide
• Synonyms: 2-(dimethoxymethyl)quinoxaline 1,4-dioxide;2-(DIMETHOXYMETHYL)CHINOXALINE-1,4-DIOXIDE
• CAS NO: 32065-66-0
• Molecular Formula: C₁₁H₁₂N₂O₄
• Molecular Weight: 236.22398
• EINECS: 250-910-9
• Mol File: 32065-66-0.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(dimethoxymethyl)quinoxaline 1,4-dioxide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(dimethoxymethyl)quinoxaline 1,4-dioxide(32065-66-0)
• EPA Substance Registry System: 2-(dimethoxymethyl)quinoxaline 1,4-dioxide(32065-66-0)

Safety Data

• Hazardous Substances Data: 32065-66-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-(dimethoxymethyl)quinoxaline 1,4-dioxide is used as an intermediate in the synthesis of Cyadox, which is an antibiotic drug. 2-(dimethoxymethyl)quinoxaline 1,4-dioxide plays a crucial role in the development of new antibiotics to combat bacterial infections.
Used in Animal Feed Industry:
2-(dimethoxymethyl)quinoxaline 1,4-dioxide has the potential to be used as a feedstuff additive in promoting the growth of animals. Its incorporation into animal feed can enhance the overall health and productivity of livestock, contributing to the efficiency of the animal feed industry.

InChI:InChI=1/C11H12N2O4/c1-16-11(17-2)10-7-12(14)8-5-3-4-6-9(8)13(10)15/h3-7,11H,1-2H3

Upstream product

• 480-96-6 benzofurazan oxide 
• 6342-56-9 Pyruvic aldehyde dimethyl acetal 
• 236092-93-6 benzofuroxane N-oxide 
• 19060-10-7 3,3-dimethoxypropanal 

Downstream Products

• 879-65-2 quinoxaline-2-carboxylic acid 
• 1593-08-4 Quinoxaline-2-carboxaldehyde 
• 65884-46-0 2-formylquinoxaline-N₁,N₄-dioxide cyanocetylhydrazone 

Relevant articles and documents

Quinoxaline - 1, 4 - dioxide in animal use in the manufacture of

The invention discloses an antibacterial derivative of a quinoxaline-1,4-dioxide and application of the antibacterial derivative in animal production. The derivative of the quinoxaline-1,4-dioxide as shown in a formula 1, a formula 2, a formula 3, a formula 4, a formula 5 or a formula 6 or a salt of the derivative has excellent antibacterial activity, is low-toxic or non-toxic to livestock, and has higher antibacterial activity and higher safety than the existing quinoxaline derivative products in the market, and therefore, the derivative of the quinoxaline-1,4-dioxide or the salt of the derivative can be used as a growth promoter for a feed to promote the growth of the livestock, and has excellent application prospect in the breeding industry.

Synthesis and Biological Evaluation of New Quinoxaline Derivatives as Antioxidant and Anti-Inflammatory Agents

We report the synthesis, anti-inflammatory, and antioxidant activities of novel quinoxaline and quinoxaline 1,4-di-N-oxide derivatives. Microwave-assisted methods have been used to optimize reaction times and to improve yields. The tested compounds presented important scavenging activities and promising in vitro inhibition of soybean lipoxygenase (LOX). Two of the best LOX inhibitors (compounds 7b and 8f) were evaluated as invivo anti-inflammatory agents using the carrageenin-induced edema model. One of them (compound 7b) showed important in vivo anti-inflammatory effect (41%) similar to that of indomethacin (47%) used as the reference drug. Synthesis and Biological Evaluation of New Quinoxaline Derivatives as Antioxidant and Anti-Inflammatory Agents Asuncion Burguete, Eleni Pontiki, Dimitra Hadjipavlou-Litina*, Saioa Ancizu, Raquel Villar, Beatriz Solano, Elsa Moreno, Enrique Torres, Silvia Perez, Ignacio Aldana and Antonio Monge The synthesis, anti-inflammatory and antioxidant activities of new quinoxaline derivatives are reported. The new compounds exhibit important scavenging activities and promising values of in vitro inhibition of soybean LOX, One of them shows strong in vivo anti-inflammatory effect similar to that of indomethacin used as the reference drug.