3184-61-0

Basic information

• Product Name: 4-(1,3-dioxoisoindol-2-yl)butanenitrile
• Synonyms: 4-(1,3-dioxoisoindol-2-yl)butanenitrile;4-(1,3-diketoisoindolin-2-yl)butyronitrile;4-(1,3-dioxo-2-isoindolinyl)butanenitrile;4-(1,3-dioxoisoindolin-2-yl)butanenitrile;4-Phthalimidobutyronitrile
• CAS NO: 3184-61-0
• Molecular Formula: C₁₂H₁₀N₂O₂
• Molecular Weight: 214.23
• Mol File: 3184-61-0.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 403.9°Cat760mmHg
• Flash Point: 198.1°C
• Appearance: /
• Density: 1.286g/cm³
• Vapor Pressure: 9.83E-07mmHg at 25°C
• Refractive Index: 1.589
• CAS DataBase Reference: 4-(1,3-dioxoisoindol-2-yl)butanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(1,3-dioxoisoindol-2-yl)butanenitrile(3184-61-0)
• EPA Substance Registry System: 4-(1,3-dioxoisoindol-2-yl)butanenitrile(3184-61-0)

Safety Data

• Hazardous Substances Data: 3184-61-0(Hazardous Substances Data)

Usage

General Description

4-(1,3-dioxoisoindol-2-yl)butanenitrile is a chemical compound with the molecular formula C11H7NO3. It is a nitrile derivative containing a butane chain attached to a dioxoisoindole ring. 4-(1,3-dioxoisoindol-2-yl)butanenitrile is often used in organic synthesis and pharmaceutical research as a building block for the synthesis of various organic compounds and pharmaceuticals. It is a white to off-white solid at room temperature and is sparingly soluble in water. Its chemical structure and properties make it suitable for use in the development of new drugs and other bioactive compounds.

InChI:InChI=1/C12H10N2O2/c13-7-3-4-8-14-11(15)9-5-1-2-6-10(9)12(14)16/h1-2,5-6H,3-4,8H2

Upstream product

• 6097-07-0 N-(pent-4-ynyl)phthalimide 
• 696-62-8 para-iodoanisole 
• 1435331-50-2 2-(5-(4-methoxyphenyl)pent-4-yn-1-yl)isoindoline-1,3-dione 

Downstream Products

• 88-99-3 benzene-1,2-dicarboxylic acid 
• 56-12-2 4-amino-n-butyric acid 
• 32754-99-7 4-aminobutyronitrile 
• 86088-63-3 N-<4-butyl>phthalimide 
• 86101-33-9 N-<(4-(N-nitroso-p-toluenesulfonamido)-1-butyl)>phthalimide 
• 86088-65-5 N-(4-hydroxy-1-butyl)phthalimide tosylate 
• 86088-64-4 N-(4-benzamido-1-butyl)phthalimide 
• 5457-30-7 4-phthalimido-1-iodobutane 
• 15544-49-7 N-(N⁴-p-toluenesulfonyl)-4-aminobutylphthalimide 
• 97961-54-1 4,6-diamino-5-(phenylazo)-2-<3-(N-phthalimido)propyl>pyrimidine 
• 110-60-1 1,4-diaminobutane 

Relevant articles and documents

Preparation method of alkyl nitrile compound

The invention discloses a preparation method of an alkyl nitrile compound. Specifically, the preparation method comprises the following step: in an organic solvent, in the presence of a protective gasand under the action of a catalyst, carrying out a reduction reaction as shown in the specification on olefin as shown in a formula I, a cyanation reagent and water, wherein the alkyl nitrile compound 1 is a compound II and/or a compound III. The preparation method provided by the invention is mild in condition, can realize hydrocyanation of olefin more safely and efficiently, and has good substrate universality and functional group compatibility.