31796-72-2

Basic information

• Product Name: (S)-(+)-α-phenyl-2-pyridylmethanol
• Synonyms: (S)-(+)-α-phenyl-2-pyridylmethanol
• CAS NO: 31796-72-2
• Molecular Weight: 185.225
• Mol File: 31796-72-2.mol
• Article Data: 133

Chemical Properties

• CAS DataBase Reference: (S)-(+)-α-phenyl-2-pyridylmethanol(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-(+)-α-phenyl-2-pyridylmethanol(31796-72-2)
• EPA Substance Registry System: (S)-(+)-α-phenyl-2-pyridylmethanol(31796-72-2)

Safety Data

• Hazardous Substances Data: 31796-72-2(Hazardous Substances Data)

Upstream product

• 1121-60-4 pyridine-2-carbaldehyde 
• 17624-36-1 2-pyridyllithium 
• 100-52-7 benzaldehyde 
• 504-29-0 2-aminopyridine 
• 91-02-1 phenyl(pyridin-2-yl)methanone 
• 98-98-6 2-Picolinic acid 
• 101-82-6 2-Benzylpyridine 
• 21970-13-8 (pyridin-2-yl)magnesium bromide 
• 130318-72-8 methyldiphenyltelluronium tetraphenylborate 
• 21948-75-4 2-methylsulfinylpyridine 
• 13737-04-7 2-(trimethylsilyl)pyridine 
• 108-86-1 bromobenzene 
• 3240-34-4 [bis(acetoxy)iodo]benzene 
• 180509-41-5 2-(phenyl(trimethylsilyl)methyl)pyridine 

Downstream Products

• 91-02-1 phenyl(pyridin-2-yl)methanone 
• 40473-17-4 2‐(chloro(phenyl)methyl)pyridine 
• 5583-33-5 (R)-(-)-α-phenyl-2-pyridylmethanol 
• 664995-22-6 P(C₆H₄CH₃)2OCH(C₆H₅)C₅H₄N 
• 1073477-82-3 2-[bromo(phenyl)methyl]pyridine 
• 74031-79-1 phenyl(pyridin-2-yl)methyl acetate 
• 151645-57-7 C₁₄H₁₃NO₂ 
• 177602-10-7 C₁₄H₁₃NO₂ 
• 5583-33-5 (S)-(+)-α-phenyl-2-pyridylmethanol 

Relevant articles and documents

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Palladium-Catalyzed Direct Arylation of 2-Pyridylmethyl Silanes with Aryl Bromides

The first palladium-catalyzed direct arylation of 2-pyridylmethyl silanes with aryl bromides to generate a diverse array of aryl(2-pyridyl)-methyl silane derivatives has been developed. This protocol facilitates access to various kinds of heterocycle-containing silanes in good to excellent yields (40 examples, 66-97% yield) with good functional group tolerance. The scalability of this transformation is demonstrated.

Amino alcohols using the optically active amino alcohol derivative bi- Nord complex boron - -

Disclosed are an amino alcohol-boron-binol complex as an intermediate, including Complex 3-1-1 shown below, and a method for preparing an optically active amino alcohol by using the same, wherein a racemic amino alcohol is resolved in an enationselective manner using a boron compound and a (R)- or (S)-binol, whereby an amino alcohol derivative with high optical purity can be prepared at high yield.

Tunable System for Electrochemical Reduction of Ketones and Phthalimides

Herein, we report an efficient, tunable system for electrochemical reduction of ketones and phthalimides at room temperature without the need for stoichiometric external reductants. By utilizing NaN3 as the electrolyte and graphite felt as both the cathode and the anode, we were able to selectively reduce the carbonyl groups of the substrates to alcohols, pinacols, or methylene groups by judiciously choosing the solvent and an acidic additive. The reaction conditions were compatible with a diverse array of functional groups, and phthalimides could undergo one-pot reductive cyclization to afford products with indolizidine scaffolds. Mechanistic studies showed that the reactions involved electron, proton, and hydrogen atom transfers. Importantly, an N3/HN3 cycle operated as a hydrogen atom shuttle, which was critical for reduction of the carbonyl groups to methylene groups.