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  • 3069-25-8 Structure
  • Basic information

    1. Product Name: N-Methylaminopropyltrimethoxysilane
    2. Synonyms: 3-TRIMETHOXYSILYL PROPYLMETHYLAMINE;(3-METHYLAMINOPROPYL)TRIMETHOXYSILANE;1-Propanamine, N-methyl-3-(trimethoxysilyl)-;CM8620;Trimethoxy[3-(methylamino)propyl]silane 97%;dynasylan1110;n-methyl-3-(trimethoxysilyl)-1-propanamin;N-methyl-3-(trimethoxysilyl)-1-Propanamine
    3. CAS NO:3069-25-8
    4. Molecular Formula: C7H19NO3Si
    5. Molecular Weight: 193.32
    6. EINECS: 221-334-5
    7. Product Categories: N/A
    8. Mol File: 3069-25-8.mol
    9. Article Data: 6
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 106 °C(lit.)
    3. Flash Point: 180 °F
    4. Appearance: /
    5. Density: 0.975 g/mL at 25 °C(lit.)
    6. Vapor Pressure: 2.448mmHg at 25°C
    7. Refractive Index: n20/D 1.421
    8. Storage Temp.: Inert atmosphere,Room Temperature
    9. Solubility: N/A
    10. PKA: 10.75±0.10(Predicted)
    11. Water Solubility: Hydrolyzes in water.
    12. Sensitive: Moisture Sensitive
    13. BRN: 2072720
    14. CAS DataBase Reference: N-Methylaminopropyltrimethoxysilane(CAS DataBase Reference)
    15. NIST Chemistry Reference: N-Methylaminopropyltrimethoxysilane(3069-25-8)
    16. EPA Substance Registry System: N-Methylaminopropyltrimethoxysilane(3069-25-8)
  • Safety Data

    1. Hazard Codes: Xi
    2. Statements: 36/37/38
    3. Safety Statements: 26-36-26/36
    4. RIDADR: UN 1993 / PGIII
    5. WGK Germany: 3
    6. RTECS:
    7. TSCA: Yes
    8. HazardClass: N/A
    9. PackingGroup: N/A
    10. Hazardous Substances Data: 3069-25-8(Hazardous Substances Data)

3069-25-8 Usage

Description

N-Methylaminopropyltrimethoxysilane, also known as (3-Methylaminopropyl)trimethoxysilane (MAPTMS), is an aminoalkyltrimethoxysilane compound that is widely utilized in various applications due to its unique properties. It is characterized by its ability to form strong covalent bonds with inorganic surfaces, such as glass, metal, and ceramics, as well as with organic materials, making it a versatile compound for surface immobilization and modification.

Uses

Used in Adhesive Industry:
N-Methylaminopropyltrimethoxysilane is used as an adhesion promoter for enhancing the bonding strength between different materials, such as metals, plastics, and glass. Its ability to form strong covalent bonds with both inorganic and organic surfaces contributes to improved adhesion and durability of the final product.
Used in Surface Modification:
In the field of surface modification, N-Methylaminopropyltrimethoxysilane is used as a coupling agent to improve the interaction between inorganic and organic materials. This can be particularly useful in the creation of composite materials, where the enhanced interaction between the components can lead to improved mechanical, thermal, and chemical properties.
Used in Coatings Industry:
N-Methylaminopropyltrimethoxysilane is also employed in the coatings industry as a component of various formulations. Its ability to bond with both inorganic and organic materials can improve the adhesion, durability, and overall performance of coatings applied to different substrates, such as metal, plastic, or concrete.
Used in Silanization Surface Immobilization:
In the field of silanization, N-Methylaminopropyltrimethoxysilane is used for surface immobilization, allowing for the attachment of various organic molecules, such as proteins, enzymes, or other biomolecules, to inorganic surfaces. This can be particularly useful in the development of biosensors, lab-on-a-chip devices, and other bioanalytical applications where the immobilization of specific molecules on a surface is required.

Check Digit Verification of cas no

The CAS Registry Mumber 3069-25-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,0,6 and 9 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 3069-25:
(6*3)+(5*0)+(4*6)+(3*9)+(2*2)+(1*5)=78
78 % 10 = 8
So 3069-25-8 is a valid CAS Registry Number.
InChI:InChI=1/C7H19NO3Si/c1-6-7(8-2)12(9-3,10-4)11-5/h7-8H,6H2,1-5H3

3069-25-8 Well-known Company Product Price

  • Brand
  • (Code)Product description
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  • Detail
  • Alfa Aesar

  • (L16541)  (3-Methylaminopropyl)trimethoxysilane, 95%   

  • 3069-25-8

  • 25g

  • 1107.0CNY

  • Detail
  • Alfa Aesar

  • (L16541)  (3-Methylaminopropyl)trimethoxysilane, 95%   

  • 3069-25-8

  • 100g

  • 3568.0CNY

  • Detail
  • Aldrich

  • (551635)  Trimethoxy[3-(methylamino)propyl]silane  97%

  • 3069-25-8

  • 551635-25ML

  • 4,347.72CNY

  • Detail

3069-25-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name N-Methylaminopropyltrimethoxysilane

1.2 Other means of identification

Product number -
Other names N-Methyl-3-(trimethoxysilyl)propylamine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:3069-25-8 SDS

3069-25-8Synthetic route

methylamine
74-89-5

methylamine

3-Chloropropyltrimethoxysilan
2530-87-2

3-Chloropropyltrimethoxysilan

N-methyl-3-trimethoxysilylpropylamine
3069-25-8

N-methyl-3-trimethoxysilylpropylamine

N-methyl-N-allylamine
627-37-2

N-methyl-N-allylamine

trimethoxysilane
2487-90-3

trimethoxysilane

A

N-methyl-3-trimethoxysilylpropylamine
3069-25-8

N-methyl-3-trimethoxysilylpropylamine

B

C7H19NO3Si

C7H19NO3Si

Conditions
ConditionsYield
With platinum(0)-1,3-divinyl-1,1,3,3-tetramethyldisiloxane complex at 80℃; for 20h; Schlenk technique; Inert atmosphere; Overall yield = 93.2 %Spectr.; regioselective reaction;
glutaric anhydride,
108-55-4

glutaric anhydride,

N-methyl-3-trimethoxysilylpropylamine
3069-25-8

N-methyl-3-trimethoxysilylpropylamine

C12H25NO6Si

C12H25NO6Si

Conditions
ConditionsYield
In tetrahydrofuran at 20℃;100%
2-Isocyanatoethyl methacrylate
30674-80-7

2-Isocyanatoethyl methacrylate

N-methyl-3-trimethoxysilylpropylamine
3069-25-8

N-methyl-3-trimethoxysilylpropylamine

3,3-dimethoxy-7-methyl-8-oxo-2-oxa-7,9-diaza-3-silaundecan-11-yl methacrylate
1560012-77-2

3,3-dimethoxy-7-methyl-8-oxo-2-oxa-7,9-diaza-3-silaundecan-11-yl methacrylate

Conditions
ConditionsYield
at 60℃;100%
N-methyl-3-trimethoxysilylpropylamine
3069-25-8

N-methyl-3-trimethoxysilylpropylamine

hexafluoroglutaric anhydride
376-68-1

hexafluoroglutaric anhydride

C12H19F6NO6Si

C12H19F6NO6Si

Conditions
ConditionsYield
In tetrahydrofuran at 20℃; for 0.5h;99%
N-methyl-3-trimethoxysilylpropylamine
3069-25-8

N-methyl-3-trimethoxysilylpropylamine

epichlorohydrin
106-89-8

epichlorohydrin

N-(2',3'-epoxypropyl)-(3-N-methylaminopropyl)-trimethoxysilane

N-(2',3'-epoxypropyl)-(3-N-methylaminopropyl)-trimethoxysilane

Conditions
ConditionsYield
With potassium carbonate In toluene for 16h; Reflux; Inert atmosphere;96%
N-methyl-3-trimethoxysilylpropylamine
3069-25-8

N-methyl-3-trimethoxysilylpropylamine

hexafluoroglutaric anhydride
376-68-1

hexafluoroglutaric anhydride

silver(l) oxide
20667-12-3

silver(l) oxide

(H3CO)3Si(CH2)3N(CH3)C(O)(CF2)3COO(1-)*Ag(1+)=Ag[(H3CO)3Si(CH2)3N(CH3)C(O)(CF2)3COO]
876734-90-6

(H3CO)3Si(CH2)3N(CH3)C(O)(CF2)3COO(1-)*Ag(1+)=Ag[(H3CO)3Si(CH2)3N(CH3)C(O)(CF2)3COO]

Conditions
ConditionsYield
In further solvent(s) under Ar, Schlenk setup, glutaric anhydride (1.4 mmol) in MTBE added to soln. of silicon compd. (1.4 mmol), stirred for 10 min, added to Ag2O (1.4 mmol) suspd. in MTBE, stirred for 18 h at room temp. in darkness; evapd. (vac.), elem. anal.;93%
N-methyl-3-trimethoxysilylpropylamine
3069-25-8

N-methyl-3-trimethoxysilylpropylamine

acetyl chloride
75-36-5

acetyl chloride

N-methyl-N-(3-(trimethoxysilyl)propyl)acetamide

N-methyl-N-(3-(trimethoxysilyl)propyl)acetamide

Conditions
ConditionsYield
Stage #1: N-methyl-3-trimethoxysilylpropylamine With trimethylamine In dichloromethane at 0℃; for 0.166667h; Inert atmosphere;
Stage #2: acetyl chloride In dichloromethane for 4.5h;
85%
N-methyl-3-trimethoxysilylpropylamine
3069-25-8

N-methyl-3-trimethoxysilylpropylamine

bis(trifluoromethanesulfonyl)amide
82113-65-3

bis(trifluoromethanesulfonyl)amide

C32H80N8O12Si8*8C2HF6NO4S2

C32H80N8O12Si8*8C2HF6NO4S2

Conditions
ConditionsYield
In water; dimethyl sulfoxide at 25 - 100℃; for 19h;84%
N-methyl-3-trimethoxysilylpropylamine
3069-25-8

N-methyl-3-trimethoxysilylpropylamine

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

N,N'-bis(trimethoxysilylpropyl)-N,N'-dimethyl-1,3-propanediamine

N,N'-bis(trimethoxysilylpropyl)-N,N'-dimethyl-1,3-propanediamine

Conditions
ConditionsYield
at 130℃; for 3h; Inert atmosphere; Industrial scale;80%
1,10-dichlorodecane
2162-98-3

1,10-dichlorodecane

N-methyl-3-trimethoxysilylpropylamine
3069-25-8

N-methyl-3-trimethoxysilylpropylamine

N,N'-bis(trimethoxysilylpropyl)-N,N'-dimethyl-1,10-decanediamine

N,N'-bis(trimethoxysilylpropyl)-N,N'-dimethyl-1,10-decanediamine

Conditions
ConditionsYield
at 130℃; for 5h; Inert atmosphere;78.8%
cyanoacetic acid chloride
16130-58-8

cyanoacetic acid chloride

N-methyl-3-trimethoxysilylpropylamine
3069-25-8

N-methyl-3-trimethoxysilylpropylamine

N-methyl-N-(3-trimethoxysilyl propyl)cyanoacetamide

N-methyl-N-(3-trimethoxysilyl propyl)cyanoacetamide

Conditions
ConditionsYield
With pyridine In diethyl ether at 20℃; for 2.5h;75%
With pyridine In diethyl ether at 20℃; for 2.5h;75%
1,5-dichloropentane
628-76-2

1,5-dichloropentane

N-methyl-3-trimethoxysilylpropylamine
3069-25-8

N-methyl-3-trimethoxysilylpropylamine

N,N'-bis(trimethoxysilylpropyl)-N,N'-dimethyl-1,5-pentanediamine

N,N'-bis(trimethoxysilylpropyl)-N,N'-dimethyl-1,5-pentanediamine

Conditions
ConditionsYield
at 130℃; for 5h; Inert atmosphere;74.8%
N-methyl-3-trimethoxysilylpropylamine
3069-25-8

N-methyl-3-trimethoxysilylpropylamine

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

N,N'-bis(trimethoxysilylpropyl)-N,N'-dimethyl-1,3-propanediamine

N,N'-bis(trimethoxysilylpropyl)-N,N'-dimethyl-1,3-propanediamine

Conditions
ConditionsYield
at 130℃; for 3h; Inert atmosphere; Industrial scale;72.8%
N-methyl-3-trimethoxysilylpropylamine
3069-25-8

N-methyl-3-trimethoxysilylpropylamine

1,4-dichlorobutane
110-56-5

1,4-dichlorobutane

N,N'-bis(trimethoxysilylpropyl)-N,N'-dimethyl-1,4-butanediamine

N,N'-bis(trimethoxysilylpropyl)-N,N'-dimethyl-1,4-butanediamine

Conditions
ConditionsYield
at 130℃; for 5h; Inert atmosphere;72.6%
at 130℃; for 5h; Inert atmosphere;72.6%
1,12-diiodododecane
24772-65-4

1,12-diiodododecane

N-methyl-3-trimethoxysilylpropylamine
3069-25-8

N-methyl-3-trimethoxysilylpropylamine

N,N'-bis(trimethoxysilylpropyl)-N,N'-dimethyl-1,12-dodecanediamine

N,N'-bis(trimethoxysilylpropyl)-N,N'-dimethyl-1,12-dodecanediamine

Conditions
ConditionsYield
at 130℃; for 5h; Inert atmosphere;67.5%
N-methyl-3-trimethoxysilylpropylamine
3069-25-8

N-methyl-3-trimethoxysilylpropylamine

1,3-chlorobromopropane
109-70-6

1,3-chlorobromopropane

N,N'-bis(trimethoxysilylpropyl)-N,N'-dimethyl-1,3-propanediamine

N,N'-bis(trimethoxysilylpropyl)-N,N'-dimethyl-1,3-propanediamine

Conditions
ConditionsYield
at 130℃; for 3h; Inert atmosphere;66.4%
at 130℃; for 3h; Inert atmosphere; Industrial scale;66.4%
1,3,5,7,9,11,14-heptaisobutyltricyclo[7.3.3.15,11]heptasiloxane-endo-3,7,14-triol
307531-92-6

1,3,5,7,9,11,14-heptaisobutyltricyclo[7.3.3.15,11]heptasiloxane-endo-3,7,14-triol

N-methyl-3-trimethoxysilylpropylamine
3069-25-8

N-methyl-3-trimethoxysilylpropylamine

N-(3-([heptaisobutyl]octasilsesquioxane)propyl)methanamine
1228187-76-5

N-(3-([heptaisobutyl]octasilsesquioxane)propyl)methanamine

Conditions
ConditionsYield
With triethylamine In acetone for 48h; Reflux;64.7%
N-methyl-3-trimethoxysilylpropylamine
3069-25-8

N-methyl-3-trimethoxysilylpropylamine

1,6-dichlorohexane
2163-00-0

1,6-dichlorohexane

N,N'-bis(trimethoxysilylpropyl)-N,N'-dimethyl-1,6-hexanediamine

N,N'-bis(trimethoxysilylpropyl)-N,N'-dimethyl-1,6-hexanediamine

Conditions
ConditionsYield
at 130℃; for 5h; Concentration; Inert atmosphere;60.9%
1,8-dibromooctane
4549-32-0

1,8-dibromooctane

N-methyl-3-trimethoxysilylpropylamine
3069-25-8

N-methyl-3-trimethoxysilylpropylamine

N,N'-bis(trimethoxysilylpropyl)-N,N'-dimethyl-1,8-octanediamine

N,N'-bis(trimethoxysilylpropyl)-N,N'-dimethyl-1,8-octanediamine

Conditions
ConditionsYield
at 130℃; for 5h; Inert atmosphere;41.7%
1,7-dichloroheptane
821-76-1

1,7-dichloroheptane

N-methyl-3-trimethoxysilylpropylamine
3069-25-8

N-methyl-3-trimethoxysilylpropylamine

N,N'-bis(trimethoxysilylpropyl)-N,N'-dimethyl-1,7-heptanediamine

N,N'-bis(trimethoxysilylpropyl)-N,N'-dimethyl-1,7-heptanediamine

Conditions
ConditionsYield
at 130℃; for 5h; Inert atmosphere;40.5%
thirane
420-12-2

thirane

N-methyl-3-trimethoxysilylpropylamine
3069-25-8

N-methyl-3-trimethoxysilylpropylamine

N-Methyl-N-(3-trimethoxy-silylpropyl)-2-amino-ethanthiol
18107-13-6

N-Methyl-N-(3-trimethoxy-silylpropyl)-2-amino-ethanthiol

Conditions
ConditionsYield
In 1,4-dioxane
N-methyl-3-trimethoxysilylpropylamine
3069-25-8

N-methyl-3-trimethoxysilylpropylamine

methyl-(3-trifluorosilanyl-propyl)-amine; compound with trifluoroborane

methyl-(3-trifluorosilanyl-propyl)-amine; compound with trifluoroborane

Conditions
ConditionsYield
With boron trifluoride diethyl etherate
4-fluorobenzylidenemalononitrile
2826-22-4

4-fluorobenzylidenemalononitrile

N-methyl-3-trimethoxysilylpropylamine
3069-25-8

N-methyl-3-trimethoxysilylpropylamine

C17H23N3O3Si

C17H23N3O3Si

Conditions
ConditionsYield
In various solvent(s)
1,5-difluoro-2,4-dinitrobenzene
327-92-4

1,5-difluoro-2,4-dinitrobenzene

N-methyl-3-trimethoxysilylpropylamine
3069-25-8

N-methyl-3-trimethoxysilylpropylamine

C13H20FN3O7Si

C13H20FN3O7Si

Conditions
ConditionsYield
In various solvent(s) at 50℃; for 0.5h;
1,5-difluoro-2,4-dinitrobenzene
327-92-4

1,5-difluoro-2,4-dinitrobenzene

N-methyl-3-trimethoxysilylpropylamine
3069-25-8

N-methyl-3-trimethoxysilylpropylamine

C20H38N4O10Si2

C20H38N4O10Si2

Conditions
ConditionsYield
In various solvent(s) at 130℃; for 2h;
N-methyl-3-trimethoxysilylpropylamine
3069-25-8

N-methyl-3-trimethoxysilylpropylamine

(1E,4E)-1,5-bis(4-fluorophenyl)penta-1,4-dien-3-one
33386-21-9, 53369-00-9

(1E,4E)-1,5-bis(4-fluorophenyl)penta-1,4-dien-3-one

C24H30FNO4Si

C24H30FNO4Si

Conditions
ConditionsYield
In various solvent(s)
N-methyl-3-trimethoxysilylpropylamine
3069-25-8

N-methyl-3-trimethoxysilylpropylamine

A

T8-(CH2CH2CH2NHCH3)8

T8-(CH2CH2CH2NHCH3)8

B

T10-(CH2CH2CH2NHCH3)10

T10-(CH2CH2CH2NHCH3)10

C

T12-(CH2CH2CH2NHCH3)12

T12-(CH2CH2CH2NHCH3)12

Conditions
ConditionsYield
With water In propan-1-ol at 60℃;
N-methyl-3-trimethoxysilylpropylamine
3069-25-8

N-methyl-3-trimethoxysilylpropylamine

1-fluoro-2-nitro-4-[(E)-2-(4-nitrophenyl)vinyl]-benzene
1221231-36-2

1-fluoro-2-nitro-4-[(E)-2-(4-nitrophenyl)vinyl]-benzene

C21H27N3O7Si
1221231-39-5

C21H27N3O7Si

Conditions
ConditionsYield
With tetraethoxy orthosilicate for 5h; Inert atmosphere; Reflux;

3069-25-8Relevant articles and documents

Study of Karstedt's Catalyst for Hydrosilylation of a Wide Variety of Functionalized Alkenes with Triethoxysilane and Trimethoxysilane

Pan, Zhenhuan,Liu, Minglun,Zheng, Chaoyue,Gao, Deqing,Huang, Wei

supporting information, p. 1227 - 1230 (2017/09/02)

The hydrosilylation is one of the most important methods for the synthesis of organosilicon compounds. Karstedt's catalyst [Ptn(H2C=CHSiMe2OSiMe2CH=CH2)m] is a kind of platinum catalyst which is widely used in the hydrosilylation. In this paper, we studied the catalytic activity of Karstedt's catalyst for the hydrogenation of olefins and especially aminated alkenes with trimethoxysilane and triethoxysilane, and demonstrated the excellent performance in terms of the yield and selectivity.

N-substituted (3-aminopropyl)trifluorosilanes and [3-(trifluorosilyl)propyl]diorganylamine-trifluoroboranes

Chernov,Bolgova,Trofimova,Albanov,Chipanina,Pestunovich,Voronkov

, p. 250 - 252 (2007/10/03)

-

Azido-silane compositions

-

, (2008/06/13)

Azido-containing silane compositions of matter useful as coupling agents in the production of polymer composite articles.

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