29823-18-5 Usage
Description
Ethyl 7-bromoheptanoate is a bromoester that serves as an alkylating agent for organic compounds. It is a colorless to pale yellow liquid and is utilized in various chemical reactions and syntheses, particularly in the production of ω-chain shortened prostaglandins.
Uses
Used in Organic Synthesis:
Ethyl 7-bromoheptanoate is used as a starting material for the synthesis of benzyl 7-iodoheptanoate, which is an important intermediate in the production of various organic compounds.
Used in Pharmaceutical Research:
Ethyl 7-bromoheptanoate is used as one of the reactants in the synthesis of diethyl 7,7′-(2,5-diiodo-1,4-phenylene)bis(oxy)diheptanoate, a compound that may have potential applications in the pharmaceutical industry.
Used in the Synthesis of Carnitine-Derived Nitrones:
Ethyl 7-bromoheptanoate is employed as one of the reagents in the synthesis of CarnDOD-7C, a carnitine-derived nitrone that has potential applications in the field of neuroprotection and the treatment of neurodegenerative diseases.
Used as an Alkylating Agent:
Ethyl 7-bromoheptanoate is used as an alkylating agent in the alkylation of ethyl 3-oxoglutarate to form 2-(6-ethoxycarbonylhexyl)-3-oxoglutarate, a key step in the synthesis of various organic compounds.
Used in the Synthesis of 1-Substituted Cyclopentadienes:
Ethyl 7-bromoheptanoate is utilized in the synthesis of 1-substituted cyclopentadienes by alkylating lithium cyclopentadienide, which are important intermediates in the production of various organic compounds and materials.
Check Digit Verification of cas no
The CAS Registry Mumber 29823-18-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,9,8,2 and 3 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 29823-18:
(7*2)+(6*9)+(5*8)+(4*2)+(3*3)+(2*1)+(1*8)=135
135 % 10 = 5
So 29823-18-5 is a valid CAS Registry Number.
InChI:InChI=1/C9H17BrO2/c1-2-12-9(11)7-5-3-4-6-8-10/h2-8H2,1H3
29823-18-5Relevant articles and documents
Process for preparing azelaic acid
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, (2021/02/19)
A process for preparing azelaic acid is disclosed. In particular, the process for preparing azelaic acid is an ozone free process. The process for preparing azelaic acid comprises a step of decarboxylation of tetra-carboxylic acid in the presence of a organic sulfonic acid.
Synthesis and Characterization of Novel Acyl-Glycine Inhibitors of GlyT2
Mostyn, Shannon N.,Carland, Jane E.,Shimmon, Susan,Ryan, Renae M.,Rawling, Tristan,Vandenberg, Robert J.
, p. 1949 - 1959 (2017/09/26)
It has been demonstrated previously that the endogenous compound N-arachidonyl-glycine inhibits the glycine transporter GlyT2, stimulates glycinergic neurotransmission, and provides analgesia in animal models of neuropathic and inflammatory pain. However, it is a relatively weak inhibitor with an IC50 of 9 μM and is subject to oxidation via cyclooxygenase, limiting its therapeutic value. In this paper we describe the synthesis and testing of a novel series of monounsaturated C18 and C16 acyl-glycine molecules as inhibitors of the glycine transporter GlyT2. We demonstrate that they are up to 28 fold more potent that N-arachidonyl-glycine with no activity at the closely related GlyT1 transporter at concentrations up to 30 μM. This novel class of compounds show considerable promise as a first generation of GlyT2 transport inhibitors.
COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF AGENTS
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Paragraph 00618; 00732, (2017/07/14)
The disclosure features amino lipids and compositions involving the same. Nanoparticle compositions include an amino lipid as well as additional lipids such as phospholipids, structural lipids, PEG lipids, or a combination thereof. Nanoparticle compositions further including therapeutic and/or prophylactic agents such as RNA are useful in the delivery of therapeutic and/or prophylactic agents to mammalian cells or organs to, for example, regulate polypeptide, protein, or gene expression.