2974-94-9 Usage
Description
4-Iododiphenyl ether, also known as bis(4-iodophenyl) ether, is a chemical compound characterized by two phenyl rings connected by an oxygen atom, each adorned with an iodine atom. This structure positions it as a versatile reactant in the synthesis of a variety of organic compounds, including pharmaceuticals, dyes, and polymers. The iodine atoms in the molecule are particularly advantageous for cross-coupling reactions and as a precursor for the synthesis of functional materials. However, it is classified as a hazardous chemical due to its potential to cause skin and eye irritation, as well as its toxic effects when inhaled or ingested, necessitating careful handling and disposal.
Uses
Used in Pharmaceutical Industry:
4-Iododiphenyl ether is used as a reactant for the synthesis of pharmaceuticals, leveraging its ability to participate in cross-coupling reactions and serve as a precursor for the development of new medicinal compounds.
Used in Dye Industry:
In the dye industry, 4-Iododiphenyl ether is utilized as a reactant for the production of various dyes, capitalizing on its chemical structure to create a range of colorants for different applications.
Used in Polymer Industry:
4-Iododiphenyl ether is employed as a building block in the synthesis of polymers, where its unique structure contributes to the development of materials with specific properties for various uses.
Used in Organic Synthesis:
4-Iododiphenyl ether is used as a reactant in organic synthesis for the creation of a wide array of organic compounds, taking advantage of its reactivity and the presence of iodine atoms for cross-coupling reactions.
Used in Material Science:
As a precursor for the synthesis of functional materials, 4-Iododiphenyl ether is instrumental in material science, where its properties can be harnessed to develop new materials with specialized functions.
Check Digit Verification of cas no
The CAS Registry Mumber 2974-94-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,9,7 and 4 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 2974-94:
(6*2)+(5*9)+(4*7)+(3*4)+(2*9)+(1*4)=119
119 % 10 = 9
So 2974-94-9 is a valid CAS Registry Number.
InChI:InChI=1/C18H13IO/c19-15-12-10-14(11-13-15)17-8-4-5-9-18(17)20-16-6-2-1-3-7-16/h1-13H
2974-94-9Relevant articles and documents
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Jorgensen,E.C. et al.
, p. 3396 - 3398 (1964)
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One-Pot, Metal-Free Conversion of Anilines to Aryl Bromides and Iodides
Leas, Derek A.,Dong, Yuxiang,Vennerstrom, Jonathan L.,Stack, Douglas E.
supporting information, p. 2518 - 2521 (2017/05/24)
A metal-free synthesis of aryl bromides and iodides from anilines via halogen abstraction from bromotrichloromethane and diiodomethane is described. This one-pot reaction affords aryl halides from the corresponding anilines in moderate to excellent yields without isolation of diazonium salts. The transformation has short reaction times, a simple workup, and insensitivity to moisture and air and avoids excess halogenation. DFT calculations support a SRN1 mechanism. This method represents a convenient alternative to the classic Sandmeyer reaction.
An in situ acidic carbon dioxide/glycol system for aerobic oxidative iodination of electron-rich aromatics catalyzed by Fe(NO3)3·9H2O
Ma, Ran,Huang, Cheng-Bin,Liu, An-Hua,Li, Xue-Dong,He, Liang-Nian
, p. 4308 - 4312 (2015/01/08)
An environmentally benign CO2/glycol reversible acidic system was developed for the iron(iii)-catalyzed aerobic oxidative iodination of electron-rich aromatics without the need for any conventional acid additive or organic solvent. Notably, moderate to high isolated yields (up to 97%) of the aryl iodides were attained with comparable regioselectivity when ferric nitrate nonahydrate was used as the catalyst with molecular iodine under 1 MPa of CO2.
