2941-56-2 Usage
General Description
2-Bromo-5-chlorobenzothiazole is a chemical compound consisting of a benzothiazole core with bromine and chlorine substituents at the 2 and 5 positions, respectively. It is commonly used as a building block in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals. It has been found to exhibit antimicrobial and antifungal properties, making it potentially useful in the development of new drugs and pesticides. Additionally, it has been investigated as a potential corrosion inhibitor for metal surfaces. However, it is important to handle this compound with care, as it is considered hazardous and may cause irritation to the skin, eyes, and respiratory system.
Check Digit Verification of cas no
The CAS Registry Mumber 2941-56-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,9,4 and 1 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 2941-56:
(6*2)+(5*9)+(4*4)+(3*1)+(2*5)+(1*6)=92
92 % 10 = 2
So 2941-56-2 is a valid CAS Registry Number.
InChI:InChI=1/C7H3BrClNS/c8-7-10-5-3-4(9)1-2-6(5)11-7/h1-3H
2941-56-2Relevant articles and documents
Design, synthesis, and SAR of cis-1,2-diaminocyclohexane derivatives as potent factor Xa inhibitors. Part I: Exploration of 5-6 fused rings as alternative S1 moieties
Yoshikawa, Kenji,Yokomizo, Aki,Naito, Hiroyuki,Haginoya, Noriyasu,Kobayashi, Shozo,Yoshino, Toshiharu,Nagata, Tsutomu,Mochizuki, Akiyoshi,Osanai, Ken,Watanabe, Kengo,Kanno, Hideyuki,Ohta, Toshiharu
experimental part, p. 8206 - 8220 (2010/04/06)
A series of cis-1,2-diaminocyclohexane derivatives were synthesized with the aim of optimizing previously disclosed factor Xa (fXa) inhibitors. The exploration of 5-6 fused rings as alternative S1 moieties resulted in two compounds which demonstrated improved solubility and reduced food effect compared to the clinical candidate, compound A. Herein, we describe the synthesis and structure-activity relationship (SAR), together with the physicochemical properties and pharmacokinetic (PK) profiles of some prospective compounds.
