29334-67-6

Basic information

• Product Name: 3-CHLORO-6-(3,5-DIMETHYL-1H-PYRAZOL-1-YL)PYRIDAZINE
• Synonyms: Pyridazine, 3-chloro-6-(3,5-dimethylpyrazol-1-yl)- (7CI,8CI);Pyridazine,3-chloro-6-(3,5-diMethyl-1H-pyrazol-1-yl)-;3-(3,5-Dimethylpyrazol-1-yl)-6-chloropyridazine;3-Chloro-6-(3,5-dimethylpyrazol-1-yl)pyridazine;NSC 270405;3-CHLORO-6-(3,5-DIMETHYL-1H-PYRAZOL-1-YL)PYRIDAZINE;3-Chloro-6-(3,5-dimethyl-1H-pyrazol-1-yl)pyridazine 90%;3-Chloro-6-(3,5-dimethyl-1H-pyrazol-1-yl)pyridazine90%
• CAS NO: 29334-67-6
• Molecular Formula: C₉H₉ClN₄
• Molecular Weight: 208.65
• Product Categories: blocks;Imidazoles;Pyridines
• Mol File: 29334-67-6.mol
• Article Data: 6

Chemical Properties

• Melting Point: 112-114
• Boiling Point: 380.2 °C at 760 mmHg
• Flash Point: 183.7 °C
• Appearance: /
• Density: 1.36 g/cm³
• Vapor Pressure: 1.21E-05mmHg at 25°C
• Refractive Index: 1.657
• PKA: -0.74±0.10(Predicted)
• CAS DataBase Reference: 3-CHLORO-6-(3,5-DIMETHYL-1H-PYRAZOL-1-YL)PYRIDAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-CHLORO-6-(3,5-DIMETHYL-1H-PYRAZOL-1-YL)PYRIDAZINE(29334-67-6)
• EPA Substance Registry System: 3-CHLORO-6-(3,5-DIMETHYL-1H-PYRAZOL-1-YL)PYRIDAZINE(29334-67-6)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22
• Hazardous Substances Data: 29334-67-6(Hazardous Substances Data)

Usage

General Description

3-Chloro-6-(3,5-dimethyl-1H-pyrazol-1-yl)pyridazine is a synthetic chemical compound. It belongs to the class of organic compounds known as pyridazines and pyridazine derivatives. Specifically, it is a member of the pyrazole subclass, characterized by a 5-membered aromatic ring containing three carbon atoms and two nitrogen atoms. The primary structure of this compound has a (3,5-dimethyl-1H-pyrazol-1-yl)pyridazine core, with a chlorine atom substituted at the 3' position of the pyridazine ring. However, information about its physical characteristics, toxicity, and potential uses appears to be limited or not readily available in the scientific literature.

InChI:InChI=1/C9H9ClN4/c1-6-5-7(2)14(13-6)9-4-3-8(10)11-12-9/h3-5H,1-2H3

Upstream product

• 67-51-6 3,5-dimethyl-1H-pyrazole 
• 141-30-0 3,6-dichlorpyridazine 
• 17284-97-8 3-Chloro-6-hydrazinopyridazine 
• 123-54-6 acetylacetone 

Downstream Products

• 1159251-27-0 3-(3,5-dimethyl-pyrazol-1-yl)-6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-pyridazine 
• 1237852-24-2 (η5-cyclopentadienyl)Ru(3-chloro-6-(3,5-dimethylpyrazolyl)pyridazine)(PPh3)PF6 
• 90442-63-0 {Rh(carbon monoxide)(triphenylphosphine)(3-(3,5-dimethylpyrazol-1-yl)-6-chloro-pyridazine)}ClO₄ 
• 90442-57-2 {Ir(carbon monoxide)(3-(3,5-dimethylpyrazol-1-yl)-6-chloro-pyridazine)(triphenylphosphine)2}ClO₄ 
• 70589-04-7 3-(3,5-dimethyl-1H-pyrazol-1-yl)-6-hydrazinylpyridazine 
• 110696-54-3 2-{2-[Benzyl-(2-phenoxy-ethyl)-amino]-ethyl}-6-(3,5-dimethyl-pyrazol-1-yl)-2H-pyridazin-3-one 
• 142230-65-7 6-(3,5-Dimethyl-pyrazol-1-yl)-2-[2-(2-phenoxy-ethylamino)-ethyl]-2H-pyridazin-3-one 
• 73259-08-2 6-(3,5-dimethyl-1H-pyrazol-1-yl)pyridazin-3(2H)-one 

Relevant articles and documents

Synthesis, crystal structures and properties of two copper (II) complexes with pyridazine derivative ligand

Two new complexes, [Cu(L)2(CH3OH)]·(ClO 4)2 (1) and [Cu(L)2(H2O)] ·(NO3)2 (2), have been synthesized and their crystal structures have been determined by X-ray analysis, where L = 3-(3,5-bimethylpyrazole-yl)-6-chloro-pyridazine]. The complex 1 crystallizes in the monoclinic, space group C2/c, and the coordination configuration of copper (II) is better described as trigonal pyramidal geometry with four N atoms from L and one O methanol . The coordination configuration of 2 is quite similar to that of 1 except Owater instead of O methanol . The intermolecular hydrogen bonds link the repeat units and extend the molecules to multinuclear structures in both compounds. The spectral properties of the title compounds have been studied and discussed. Furthermore, the antibacterial activities of the title compounds have been detected, the results indicate that the ligands and two copper(II) complexes exhibit certain fungicidal activities again several bacteria.

Synthesis, antibacterial and antioxidant properties of pyrazolylpyridazines

A number of 6-chloro-3-(pyrazol-1′-yl) pyridazines were prepared from 3,6-dichloropyridazine via either reaction with hydrazine followed I by reaction with appropriate reagents to develop the pyrazole or through a nucleophilic reaction with a pyrazole. So

Synthesis of amide derivatives of [6-(3,5-dimethylpyrazol-1-yl)-3(2H)- pyridazinone-2-yl]acetic acid and their analgesic and anti-inflammatory properties

A series of structurally different amide derivatives of [6-(3,5-dimethylpyrazol-1-yl)-3(2H)-pyridazinone-2-yl] acetic acid were prepared and tested for their analgesic and anti-inflammatory activity in vivo by using p-benzoquinone-induced writhing test an