2881-53-0Relevant articles and documents
Catalyst- and Reagent-Free Electrochemical Azole C?H Amination
Qiu, Youai,Struwe, Julia,Meyer, Tjark H.,Oliveira, Jo?o C. A.,Ackermann, Lutz
supporting information, p. 12784 - 12789 (2018/09/10)
Catalyst- and chemical oxidant-free electrochemical azole C?H aminations were accomplished via cross-dehydrogenative C?H/N?H functionalization. The catalyst-free electrochemical C?H amination proved feasible on azoles with high levels of efficacy and selectivity, avoiding the use of stoichiometric oxidants under ambient conditions. Likewise, the C(sp3)?H nitrogenation proved viable under otherwise identical conditions. The dehydrogenative C?H amination featured ample scope, including cyclic and acyclic aliphatic amines as well as anilines, and employed sustainable electricity as the sole oxidant.
The synthesis of 2-Aminobenzoxazoles using reusable ionic liquid as a green catalyst under mild conditions
Zhou, Ya,Liu, Zhiqing,Yuan, Tingting,Huang, Jianbin,Liu, Chenjiang
supporting information, (2017/04/10)
A facile, green, and efficient method for the direct oxidative amination of benzoxazoles using heterocyclic ionic liquid as catalyst has been developed. The reaction proceeded smoothly at room temperature and gave the desirable 2-Aminobenzoxazoles with good to excellent yields (up to 97%). The catalyst 1-butylpyridinium iodide can be easily recycled and reused with similar efficacies for at least four cycles.
Practical approach for synthesis of 2-amino-benzoxazole in water
Cao, Ke,Wang, Jia-Ling,Wang, Lin-Hui
supporting information, p. 1471 - 1475 (2015/05/20)
A practical copper-catalyzed amination of benzoxazole with secondary amine in water has been developed. This reaction has proved to be effective to some cyclic amines, and the substituted group of nitrogen has a great impact on the amination reaction. A copper-catalyzed/amine-induced ring opening of the benzoxazole and recyclization/oxidation mechanism was also proposed.