28458-93-7Relevant articles and documents
Catalytic Direct Cyanomethylenation of C(sp3)–H Bonds via a One-Step Double C–C Bond Formation
Bhadra, Sukalyan,Kumar, Jogendra,Singh, Anupam Kumar
supporting information, p. 1512 - 1517 (2022/01/27)
An elegant and catalytic procedure for the one-step cyanomethylenation of C(sp3)–H bonds adjacent to benzazoles and ketones is described herein using DMF as a C-1 unit and TMSCN as the cyanide source. The copper-mediated reaction between DMF an
Photoinduced remote heteroaryl migration accompanied by cyanoalkylacylation in continuous flow
Duan, Xiu,Guo, Kai,Liu, Jie,Ma, Can-Liang,Qin, Long-Zhou,Qiu, Jiang-Kai,Sun, Qi,Wu, Meng-Yu,Yuan, Xin,Zhang, Xin-Peng,Zhu, Shan-Shan
supporting information, p. 8916 - 8921 (2021/11/27)
A photoinduced 1,4-heteroaryl migration from a carbon center to a nitrogen center accompanied by a cyanoalkylacylation of heterocyclic-substituted azidyl homoallylic alcohols and cycloketone oxime esters has been described. This simple and powerful protoc
Synthesis method of 2-aryl formyl benzoxazole compound
-
Paragraph 0046-0052, (2021/06/21)
The invention discloses a synthesis method of a 2-aryl formyl benzoxazole compound, which comprises the following steps: in an oxygen-containing atmosphere and an ultrasonic environment, carrying out intramolecular cyclization-oxidation cascade reaction on N-(2-hydroxyphenyl)-2-aryl acetamide under the synergistic catalysis action of an acidic eutectic solvent and a cuprous salt, thereby obtaining the 2-aryl formyl benzoxazole compound. The method is mild in reaction condition, simple in step, green, energy-saving, high in reaction selectivity and product yield and excellent in substrate functional group compatibility, the acidic eutectic solvent/cuprous salt catalytic system can be recycled for multiple times, and the production cost is greatly reduced.
