280762-56-3

Basic information

• Product Name: 4-(hydroxymethyl)-5-{[(4-methoxybenzyl)oxy]methyl}-2-methyl-3-pyridinol
• Synonyms: 4-(hydroxymethyl)-5-{[(4-methoxybenzyl)oxy]methyl}-2-methyl-3-pyridinol
• CAS NO: 280762-56-3
• Molecular Weight: 289.331
• Mol File: 280762-56-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(hydroxymethyl)-5-{[(4-methoxybenzyl)oxy]methyl}-2-methyl-3-pyridinol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(hydroxymethyl)-5-{[(4-methoxybenzyl)oxy]methyl}-2-methyl-3-pyridinol(280762-56-3)
• EPA Substance Registry System: 4-(hydroxymethyl)-5-{[(4-methoxybenzyl)oxy]methyl}-2-methyl-3-pyridinol(280762-56-3)

Safety Data

• Hazardous Substances Data: 280762-56-3(Hazardous Substances Data)

Upstream product

• 824-94-2 p-methoxybenzyl chloride 
• 1136-52-3 (2,2,8-trimethyl-4H-[1,3]dioxino[4,5-c]pyridin-5-yl)methanol 
• 252987-03-4 5-{[(4-methoxybenzyl)oxy]methyl}-2,2,8-trimethyl-4H-[1,3]dioxino[4,5-c]pyridine 

Downstream Products

• 280762-57-4 (3-(benzyloxy)-5-{[(4-methoxybenzyl)oxy]methyl}-2-methyl-4-pyridinyl)methanol 
• 280762-69-8 acetic acid 5-benzyloxy-4-chloromethyl-6-methyl-pyridin-3-ylmethyl ester 
• 280762-68-7 [5-(benzyloxy)-4-(chloromethyl)-6-methyl-3-pyridinyl]methanol 

Relevant articles and documents

Transformation of vitamin B6 to (+)-deoxypyridinoline, a useful biochemical marker for diagnosis of bone diseases

A versatile chiral synthesis of the cross-link (+)-deoxypyridinoline (Dpd, 2) was achieved starting from vitamin B6 (7). The key steps in the synthesis of (+)-2 are transformation of B6 (7) to the chloride (3d) and construction of three α-amino acid chains by utilizing (R)-(-)-Schollkopf's reagent (4), Wittig reagent (R)-(-)-5, and iodide (5)-(-)-6. (+)-Dpd (2) is a degradation product of bone collagen and has been found to be a useful marker for diagnosis of osteoporosis and other metabolic bone diseases. (C) 2000 Elsevier Science Ltd.