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272105-42-7

Disitertide, a synthetic peptide consisting of 17 amino acids, is a potent inhibitor of transforming growth factor beta (TGF-β), a key mediator of fibrosis and inflammation. Its ability to block TGF-β actions makes it a promising candidate for therapeutic intervention in various fibrotic and inflammatory conditions.

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  • L-Asparagine,L-threonyl-L-seryl-L-leucyl-L-a-aspartyl-L-alanyl-L-seryl-L-isoleucyl-L-isoleucyl-L-tryptophyl-L-alanyl-L-methionyl-L-methionyl-L-glutaminyl-

    Cas No: 272105-42-7

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  • Shandong Hanjiang Chemical Co., Ltd.
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  • L-Asparagine,L-threonyl-L-seryl-L-leucyl-L-a-aspartyl-L-alanyl-L-seryl-L-isoleucyl-L-isoleucyl-L-tryptophyl-L-alanyl-L-methionyl-L-methionyl-L-glutaminyl-

    Cas No: 272105-42-7

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  • Hangzhou J&H Chemical Co., Ltd.
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  • 272105-42-7 Structure

  • Basic information

    1. Product Name: Disitertide
    2. Synonyms: disitertide;L-Threonyl-L-seryl-L-leucyl-L-alpha-aspartyl-L-alanyl-L-seryl-L-isoleucyl-L-isoleucyl-L-tryptophyl-L-alanyl-L-methionyl-L-methionyl-L-glutaminyl-L-asparagine
    3. CAS NO:272105-42-7
    4. Molecular Formula: C68H109N17O22S2
    5. Molecular Weight: 1580.82
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 272105-42-7.mol
    9. Article Data: 0

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 1968.718 °C at 760 mmHg
    3. Flash Point: 1144.439 °C
    4. Appearance: /
    5. Density: 1.327
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 3.15±0.10(Predicted)
    10. CAS DataBase Reference: Disitertide(CAS DataBase Reference)
    11. NIST Chemistry Reference: Disitertide(272105-42-7)
    12. EPA Substance Registry System: Disitertide(272105-42-7)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 272105-42-7(Hazardous Substances Data)

272105-42-7 Usage

Uses

Used in Pharmaceutical Industry:
Disitertide is used as a therapeutic agent for its potential to treat conditions characterized by fibrosis and inflammation. By inhibiting TGF-β, it may help reduce fibrosis and inflammation, potentially slowing disease progression and improving patient outcomes.
Used in Pulmonary Fibrosis Treatment:
Disitertide is used as an antifibrotic agent for pulmonary fibrosis, aiming to alleviate the symptoms and slow the progression of the disease by reducing lung tissue scarring.
Used in Chronic Kidney Disease Management:
In chronic kidney disease, Disitertide is used as a renoprotective agent to mitigate the effects of fibrosis and inflammation on kidney function, potentially delaying the progression to end-stage renal disease.
Used in Diabetic Nephropathy Therapy:
Disitertide is utilized as a treatment for diabetic nephropathy, where it may help to reduce the renal fibrosis and inflammation associated with diabetes, thus preserving kidney health and function.
Used in Other Fibrotic Disease Research:
Disitertide is used as a research compound in preclinical studies for the treatment of various fibrotic diseases, showcasing its potential as a broad-spectrum therapeutic agent for fibrosis-related conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 272105-42-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,7,2,1,0 and 5 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 272105-42:
(8*2)+(7*7)+(6*2)+(5*1)+(4*0)+(3*5)+(2*4)+(1*2)=107
107 % 10 = 7
So 272105-42-7 is a valid CAS Registry Number.

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