267-54-9 Usage
Description
[1,3]Dioxolo[4,5-f]-2,1-benzisoxazole(8CI,9CI) is a chemical compound with the molecular formula C8H5NO2. It is a benzisoxazole derivative featuring a dioxolane ring fused to the benzene ring. This unique structure and its properties make it a compound of interest, particularly in the pharmaceutical industry. It may possess various medicinal properties, such as anti-inflammatory or analgesic effects, although further research and testing are required to confirm these potential uses and effects.
Uses
Used in Pharmaceutical Industry:
[1,3]Dioxolo[4,5-f]-2,1-benzisoxazole(8CI,9CI) is used as a potential active pharmaceutical ingredient (API) for its possible medicinal properties. [1,3]Dioxolo[4,5-f]-2,1-benzisoxazole(8CI,9CI)'s unique structure may contribute to its effectiveness in treating various conditions, such as inflammation or pain.
Used in Research and Development:
In the field of medicinal chemistry, [1,3]Dioxolo[4,5-f]-2,1-benzisoxazole(8CI,9CI) serves as a valuable compound for research and development. Scientists and researchers can use this compound to study its properties, interactions with biological systems, and potential applications in drug discovery and design.
Used in Drug Synthesis:
[1,3]Dioxolo[4,5-f]-2,1-benzisoxazole(8CI,9CI) may also be used as a key intermediate or building block in the synthesis of more complex pharmaceutical compounds. Its unique structure can be exploited to create novel drugs with improved efficacy, safety, or other desirable characteristics.
Check Digit Verification of cas no
The CAS Registry Mumber 267-54-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 2,6 and 7 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 267-54:
(5*2)+(4*6)+(3*7)+(2*5)+(1*4)=69
69 % 10 = 9
So 267-54-9 is a valid CAS Registry Number.
InChI:InChI=1/C8H5NO3/c1-5-3-12-9-6(5)2-8-7(1)10-4-11-8/h1-3H,4H2
267-54-9Relevant articles and documents
Palladium-catalyzed carbonylative cyclization of benzyl chlorides with anthranils for the synthesis of 3-arylquinolin-2(1: H)-ones
Liu, Jian-Li,Xu, Ren-Rui,Wang, Wei,Qi, Xinxin,Wu, Xiao-Feng
supporting information, p. 3584 - 3588 (2021/05/04)
An efficient carbonylative procedure for the synthesis of 3-arylquinoin-2(1H)-ones has been established. Through a palladium-catalyzed aminocarbonylation of benzyl chlorides with anthranils, a variety of 3-arylquinoin-2(1H)-one products were obtained in moderate to excellent yields with good functional group tolerance. This journal is
I2-DMSO mediated oxidative amidation of methyl ketones with anthranils for the synthesis of: α -ketoamides
Zhuang, Shi-Yi,Tang, Yong-Xing,Chen, Xiang-Long,Wu, Yan-Dong,Wu, An-Xin
supporting information, p. 4258 - 4262 (2021/05/31)
An I2-DMSO mediated oxidative amidation of methyl ketones using anthranils as masked N-nucleophiles has been developed for the direct synthesis of α-ketoamides with high atom-economy. This metal-free process involves reductive N-O bond cleavage of anthranils and oxidative C-N bond formation of methyl ketones under mild conditions. The iodo group and electrophilic formyl group provide multiple possibilities for further functionalization of α-ketoamides.
Gold-Catalyzed Intermolecular Formal [4 + 2 + 2]-Cycloaddition of Anthranils with Allenamides
Wang, Cheng,Xu, Guangyang,Shao, Ying,Tang, Shengbiao,Sun, Jiangtao
supporting information, p. 5990 - 5994 (2020/08/12)
The construction of eight-membered rings is a challenging issue due to unfavorable transannular strain and entropic barriers. We report herein a gold-catalyzed formal [4 + 2 + 2] cycloaddition reaction of anthranils with allenamides to deliver oxa-bridged eight-membered heterocycles in accepted yields with unique E/Z configuration. Moreover, the asymmetric [4 + 2 + 2] cycloaddition by using chiral phosphoramidite gold catalyst has also been conducted.
