26693-24-3

Basic information

• Product Name: 2,4-Dimethyloxazole
• Synonyms: kahweofuran;TomatoLycopene;Spicery;2,3-Dihydro-6-methylthieno[2,3-c]furan;6-Methyl-2,3-dihydrothieno[2,3-c]furan;N-Piperidinyl-3-Methylthio-1-propene
• CAS NO: 26693-24-3
• Molecular Formula: C₇H₈OS
• Molecular Weight: 140.2
• Product Categories: Flavor
• Mol File: 26693-24-3.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 193℃
• Flash Point: 70℃
• Appearance: /
• Density: 1.197
• Vapor Pressure: 0.663mmHg at 25°C
• Refractive Index: 1.582
• CAS DataBase Reference: 2,4-Dimethyloxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Dimethyloxazole(26693-24-3)
• EPA Substance Registry System: 2,4-Dimethyloxazole(26693-24-3)

Safety Data

• Hazardous Substances Data: 26693-24-3(Hazardous Substances Data)

Usage

General Description

2,4-Dimethyloxazole is a chemical compound with the molecular formula C5H7NO. It is a heterocyclic organic compound containing both nitrogen and oxygen atoms. 2,4-Dimethyloxazole is commonly used as a building block in the synthesis of various pharmaceuticals and agrochemicals. Its structure and properties make it suitable for use as a ligand in coordination chemistry and as a precursor for the formation of other organic compounds. 2,4-Dimethyloxazole is also known for its fluorescent properties, which have led to its use in the development of fluorescent probes and sensors for biological and environmental applications. However, it is important to handle and use this compound with caution, as it can be toxic and harmful if not properly managed.

InChI:InChI=1/C7H8OS/c1-5-7-6(4-8-5)2-3-9-7/h4H,2-3H2,1H3

Upstream product

• 100103-47-7 3-Brom-4-(2-bromethyl)-2-methylfuran 
• 876189-92-3 1-[3-(hydroxymethyl)-2-thienyl]-1-ethanol 
• 1448174-96-6 C₁₂H₁₈O₃S 
• 1448174-95-5 C₁₀H₁₆O₂S 
• 1448174-94-4 C₅H₈OS 
• 14189-41-4 4,5-dihydro-thiophene-3-carboxylic acid methyl ester 
• 100103-45-5 3-Brom-4-(2-iodethyl)furan 
• 100188-42-9 3-Brom-4-(2-bromethyl)furan 
• 100103-42-2 2-(4-Brom-3-furyl)ethanol 
• 206061-44-1 Benzoic acid 2-acetyl-1-oxo-tetrahydro-1λ⁴-thiophen-3-ylmethyl ester 

Relevant articles and documents

The conundrum of odourless Kahweofuran, a roasting “flavour” of coffee

A new synthesis of the dihydrothieno [2,3-c]furan Kahweofuran, isolated from coffee extracts, reveals it probably does not possess the intense and ‘violent’ sulfurous odour previously ascribed to it. We speculate that trace amounts of thiol compound(s) present as impurities in the original isolate and perhaps in other synthetic samples are instead responsible. Key steps in the present approach are a 5-endo-dig iodocyclisation to establish the furan ring and a final, highly efficient copper-catalysed intramolecular C–S bond formation of the intermediate 3-iodofuran.

Production of kahweofuran or its derivatives (by machine translation)

Efficient synthesis of [be] kahweofuran or derivatives thereof. 3 - Hydroxy methylthiophene 2 position of the hydroxyalkyl group is introduced into the [a], 3 position hydroxyl protecting group to introduce substituents, hydroxy substituents at the 2 oxidation process, hydroxyl group deprotection step 3 substituted, in the presence of a transition metal catalyst obtained in the intermediate ring (6) and a step of reducing a compound comprising a manufacturing method. [Drawing] no (by machine translation)

Rapid synthesis of kahweofuran and its derivatives, the coffee aroma components

Kahweofuran, as an impact flavor component of roasted coffee and possesses the 6-methyl-2,3-dihydrothieno[2,3-c]furan structure, was rapidly synthesized from 2-acetyl-3-hydroxymethylthiophene by the formal reductive cyclization using the Wilkinson's catalyst. Similarly, the syntheses of the 4-methyl, 6-ethyl and 4,6-dimethyl derivatives were also achieved in favorable yields.