265975-39-1Relevant articles and documents
Selective cleavage of tert-butyldimethylsilylethers ortho to a carbonyl group by ultrasound
De Groot, Alex H.,Dommisse, Roger A.,Lemière, Guy L.
, p. 1541 - 1549 (2007/10/03)
A general method for the selective cleavage of tert- butyldimethylsilylethers ortho to a carbonyl group is established by sonication of a 0.1 M solution of the substrate in 1/1 (v/v) CH3OH/CCl4. Other phenolic tert-butyldimethylsilylethers are unaffected. This reaction performed on flavanoids is completed within 3 h and no special workup is required. Other substrates are also investigated and a mechanism is proposed. (C) 2000 Elsevier Science Ltd.