26113-44-0

Basic information

• Product Name: 3-METHOXYBENZAMIDINE HYDROCHLORIDE
• Synonyms: 3-METHOXYBENZAMIDINE HYDROCHLORIDE;3-METHOXYBENZAMIDINE HYDROCHLORIDE, 95+%;m33012;3-Methoxybenzimidamide hydrochloride;3-methoxybenzene-1-carboximidamide hydrochloride
• CAS NO: 26113-44-0
• Molecular Formula: C₈H₁₀N₂O*ClH
• Molecular Weight: 186.64
• Mol File: 26113-44-0.mol
• Article Data: 1

Chemical Properties

• Melting Point: 165-166 °C
• Boiling Point: 299.8°C at 760 mmHg
• Flash Point: 135.1°C
• Appearance: /
• Vapor Pressure: 0.000874mmHg at 25°C
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: 3-METHOXYBENZAMIDINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-METHOXYBENZAMIDINE HYDROCHLORIDE(26113-44-0)
• EPA Substance Registry System: 3-METHOXYBENZAMIDINE HYDROCHLORIDE(26113-44-0)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 26113-44-0(Hazardous Substances Data)

Usage

Chemical Properties

White solid

Uses

3-Methoxybenzamidine, HCl

InChI:InChI=1/C8H10N2O.ClH/c1-11-7-4-2-3-6(5-7)8(9)10;/h2-5H,1H3,(H3,9,10);1H

Upstream product

• 1527-89-5 3-methoxybenzonitrile 

Downstream Products

• 1208259-21-5 2-(3-methoxyphenyl)quinazoline 
• 66744-02-3 4-chloro-2-(3-methoxy-phenyl)-6-methyl-pyrimidine 
• 59153-22-9 3,5-bis(3-methoxyphenyl)-1H-1,2,4-triazole 
• 1095482-30-6 2-(3-methoxyphenyl)pyrimido[5,4-b]indolizine 
• 1095482-17-9 2-(3-methoxyphenyl)-5-(pyridin-2-ylmethyl)pyrimidin-4(3H)-one 
• 1189520-20-4 (E)-5-(3-nitrobenzylidene)-2-(3-methoxyphenyl)-5,6-dihydropyrimidin-4(3H)-one 
• 1189520-21-5 (E)-5-(3-methoxybenzylidene)-2-(3-methoxyphenyl)-5,6-dihydropyrimidin-4(3H)-one 
• 1189520-13-5 (E)-5-(2-bromobenzylidene)-2-(3-methoxyphenyl)-5,6-dihydropyrimidin-4(3H)-one 
• 1189520-17-9 (E)-5-(4-fluorobenzylidene)-2-(3-methoxyphenyl)-5,6-dihydropyrimidin-4(3H)-one 
• 1189520-14-6 (E)-5-(2-chlorobenzylidene)-2-(3-methoxyphenyl)-5,6-dihydropyrimidin-4(3H)-one 
• 1189520-15-7 (E)-5-(4-methoxybenzylidene)-2-(3-methoxyphenyl)-5,6-dihydropyrimidin-4(3H)-one 
• 1189520-16-8 (E)-5-(4-chlorobenzylidene)-2-(3-methoxyphenyl)-5,6-dihydropyrimidin-4(3H)-one 
• 1189520-12-4 (E)-5-benzylidene-2-(3-methoxyphenyl)-5,6-dihydropyrimidin-4(3H)-one 
• 1189520-19-1 (E)-5-(3,5-dimethylbenzylidene)-2-(3-methoxyphenyl)-5,6-dihydropyrimidin-4(3H)-one 

Relevant articles and documents

Facile synthesis of 3,5-diaryl-1,2,4-triazoles via copper-catalyzed domino nucleophilic substitution/oxidative cyclization using amidines or imidates as substrates

Two methods for the synthesis of 3,5-diaryl-1,2,4-triazoles, both domino reactions, are reported. The first procedure, the Cu(OTf)2-catalyzed reaction between two amidines using NaHCO3 as a base, 1,10-phenanthroline as an additive and K3[Fe(CN)6]/ atmospheric oxygen as the oxidant, delivers 3,5-diaryl-1,2,4-triazoles with yields up to 68%. The second procedure for the synthesis of 3,5-diaryl-1,2,4- triazoles with yields up to 64% rests on the Cu(OTf)2-catalyzed reaction between two imidates and ammonium carbonate. This method features the formation of three bonds in a single synthetic step.