261-05-2Relevant articles and documents
INTRAMOLECULAR NITRENE INSERTIONS INTO AROMATIC AND HETEROAROMATIC RINGS. PART 8. FLASH VACUUM PYROLYSIS OF 2-AZIDOBENZYLPYRIDINES
Hicks, Martin G.,Jones, Gurnos.,York, David C.
, p. 69 - 76 (2007/10/02)
Flash vacuum pyrolysis of 2-azidobenzylpyridines (9)-(11) at temperatures from 350 to 700 deg C gave mixtures of benzonaphthyridines and their dihydro derivatives as major products.The 3-pyridyl derivative (10) also gave 2-(3-cyanoprop-1-enyl)indole (19).Benzonaphthyridines were also obtained by pyrolysis of 2-aminophenyl(x-pyridyl)methanols (4), (5), and (6), .Treatment of the azides (9)-(11) with aluminium chloride gave the corresponding 2-amino-5-chlorobenzylpyridines (21)-(23).The mechanism of the reaction is discussed.