259737-16-1

Basic information

• Product Name: 4-oxo-4-pyridin-4-yl-butyralcohol
• CAS NO: 259737-16-1
• Molecular Weight: 165.192
• Mol File: 259737-16-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-oxo-4-pyridin-4-yl-butyralcohol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-oxo-4-pyridin-4-yl-butyralcohol(259737-16-1)
• EPA Substance Registry System: 4-oxo-4-pyridin-4-yl-butyralcohol(259737-16-1)

Safety Data

• Hazardous Substances Data: 259737-16-1(Hazardous Substances Data)

Upstream product

• 96-48-0 4-butanolide 
• 1120-87-2 4-bromopyridin 

Relevant articles and documents

Synthesis and monoamine oxidase B substrate properties of 1-methyl-4-heteroaryl-1,2,3,6-tetrahydropyridines

Six analogues of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine [MPTP, (1)Scheme 1MAO-B catalyzed oxidation of MPTP.] bearing various heteroaryl groups at C-4 were synthesized and examined for their monoamine oxidase B substrate properties. The C-4 substituents include the 1-ethylpyrrol-2-yl, 1-propylpyrrol-2-yl, 1-isopropylpyrrol-2-yl, 1-cyclopropylpyrrol-2-yl, 3-ethylfuran-2-yl and 3-ethylthien-2-yl groups. The results provide information concerning steric and polar interactions between the C-4 substituent and the active site of MAO-B that are transmitted to the position of oxidation at C-6 of the tetrahydropyridinyl moiety. Copyright (C) 1999 Elsevier Science Ltd.