258516-89-1

Basic information

• Product Name: FOSPROPOFOL
• Synonyms: FOSPROPOFOL;Methanol, (2,6-bis(1-methylethyl)phenoxy)-, dihydrogen phosphate;Unii-lz257rzp7k;1-[2,6-Bis(1-methylethyl)phenoxy]methanol 1-(dihydrogen phosphate);Methanol,1-[2,6-bis(1-Methylethyl)phenoxy]-, 1-(dihydrogen phosphate)
• CAS NO: 258516-89-1
• Molecular Formula: C₁₃H₂₁O₅P
• Molecular Weight: 288.278
• Mol File: 258516-89-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Density: 1.205
• CAS DataBase Reference: FOSPROPOFOL(CAS DataBase Reference)
• NIST Chemistry Reference: FOSPROPOFOL(258516-89-1)
• EPA Substance Registry System: FOSPROPOFOL(258516-89-1)

Safety Data

• Hazardous Substances Data: 258516-89-1(Hazardous Substances Data)

Usage

Uses

Procedural sedation.

Upstream product

• 258516-82-4 2-(chloromethoxy)-1,3-diisopropylbenzene 
• 2944-52-7 2,6-diisopropyl anisole 
• 2078-54-8 2,6-diisopropylphenol 

Relevant articles and documents

Synthesis method and application of propofol sodium and intermediate thereof

The method comprises an intermediate B and an intermediate C, and, the application of the phosphorus propofol sodium prepared by the synthesis method in an animal anesthetic sedative. The phosphorus propofol sodium synthesis method provided by the invention avoids the use of highly toxic reagent chlorobromomethane and is high in safety. The prepared propofol intermediate reaction condition is mild, the operation is simple and convenient, the quality yield is ＞ 97%, and the propofol prodrug synthesized by the synthetic method provided by the invention can generate the same clinical effect as the commercially available propofol emulsion injection.