254112-80-6Relevant articles and documents
On the question of the diastereoselective alkylation of 4-unsubstituted 3-amino β-lactams. A concise synthesis of α-branched α-amino β-lactams and their coupling with α-amino acid esters
Palomo, Claudio,Aizpurua, Jesus M.,Galarza, Regina,Benito, Ana,Khamrai, Uttam K.,Eikeseth, Unni,Linden, Anthony
, p. 5563 - 5570 (2007/10/03)
The reaction of [(4S)-2-oxo-4-phenyloxazolidin-3-yl]acetic acid chloride with N-methylidene-bis-[(trimethylsilyl)methyl]amine and triethylamine in refluxing chloroform leads to a 4-unsubstituted β-lactam able to undergo highly asymmetric alkylations at th