2529-45-5 Usage
Description
Flugestone 17-acetate is a synthetic progesterone, a hormone that plays a crucial role in the reproductive system of mammals. It is chemically derived and designed to mimic the effects of natural progesterone, offering a controlled and predictable approach to managing reproductive processes in certain animal species.
Uses
Used in Veterinary Reproductive Management:
Flugestone 17-acetate is used as a hormonal treatment for inducing oestrus synchronisation in goats and sheep. This application is particularly valuable in the agricultural industry for enhancing the efficiency of breeding programs. By synchronizing the oestrus cycle in these animals, it becomes easier to manage mating schedules, improve the success rate of conception, and ultimately increase the productivity of livestock operations. This controlled approach to reproduction is essential for maintaining genetic diversity, optimizing herd health, and ensuring the economic viability of farming enterprises.
Check Digit Verification of cas no
The CAS Registry Mumber 2529-45-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,5,2 and 9 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 2529-45:
(6*2)+(5*5)+(4*2)+(3*9)+(2*4)+(1*5)=85
85 % 10 = 5
So 2529-45-5 is a valid CAS Registry Number.
InChI:InChI=1/C23H31FO5/c1-13(25)22(29-14(2)26)10-8-17-18-6-5-15-11-16(27)7-9-20(15,3)23(18,24)19(28)12-21(17,22)4/h11,17-19,28H,5-10,12H2,1-4H3/t17-,18-,19-,20-,21-,22-,23-/m0/s1
2529-45-5Relevant articles and documents
Preparation method of flurogestone acetate
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Paragraph 0013; 0014; 0015, (2017/12/13)
The invention discloses a preparation method of flurogestone acetate. The preparation method comprises the following steps: using 9a-cortisone bifluoride as a raw material, dissolving 9a-cortisone bifluoride into an organic solvent, and reacting with acyl chloride under the existence of an acid-binding agent to obtain a 9a-cortisone bifluoride-21-O-ester; then reacting the ester with sodium iodide and a sulfur-containing reducing agent in the organic solvent for deesterification, and synthesizing flugestone; and finally reacting the flugestone with acetylchloride or acetic anhydride in the organic solvent, and synthesizing flurogestone acetate. According to the preparation method, 9a-cortisone bifluoride is used as the raw material, flurogestone acetate is synthesized through three-step reaction of 21-site esterification, then reduction and de-esterification and finally 17-site ethyl esterification, and compared with a traditional synthetic method for using a mold removal object acquired through diosgenin processing as a raw material, the preparation method has the advantages such as wide raw material source, short synthetic route, simple, convenient and environmentally-friendly process, few invested equipment and high product yield, and the production cost in the method is reduced by 25% to 30% as compared with a traditional method; and a solvent used in the production can be recycled and circularly used, and is easy for industrial production.