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2516-05-4

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2516-05-4 Usage

Chemical Properties

dark green powder

Check Digit Verification of cas no

The CAS Registry Mumber 2516-05-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,5,1 and 6 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 2516-05:
(6*2)+(5*5)+(4*1)+(3*6)+(2*0)+(1*5)=64
64 % 10 = 4
So 2516-05-4 is a valid CAS Registry Number.
InChI:InChI=1/C14H12N2OS/c1-16(2)9-3-5-11-13(7-9)18-14-8-10(17)4-6-12(14)15-11/h3-8H,1-2H3

2516-05-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 7-(dimethylamino)phenothiazin-3-one

1.2 Other means of identification

Product number -
Other names Methylene Violet

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:2516-05-4 SDS

2516-05-4Downstream Products

2516-05-4Relevant articles and documents

Effect of alkali on methylene blue (C.I. Basic Blue 9) and other thiazine dyes

Mills, Andrew,Hazafy, David,Parkinson, John,Tuttle, Tell,Hutchings, Michael G.

, p. 149 - 155 (2011)

A detailed study of the action of alkali on methylene blue (C.I. Basic Blue 9) and other thiazine dyes was carried out through a combination of UV/visible spectroscopy, thin layer chromatography, mass and NMR spectrometry and computational methods. In 0.1 M aq alkali solution, methylene blue forms a highly coloured, lipophilic species that is mainly Bernthsen's methylene violet i.e. a hydrolysis decomposition product, this being contrary to the report of a red N-hydroxy methylene blue adduct. The nature of the heterocyclic nitrogen atom in C.I. Basic Blue 9 is discussed and it is concluded there is no basis for the proposal of nucleophile addition at this site of the dye. In contrast, other thiazine dyes are deprotonated by alkali to form their neutral, highly coloured, lipophilic conjugate base forms.

MULTIFUNCTIONAL RADICAL QUENCHERS FOR THE TREATMENT OF MITOCHONDRIAL DYSFUNCTION

-

Page/Page column 53, (2012/10/18)

The present disclosure provides methods for identifying therapeutic agents that are multifunctional radical quenchers. It also provides compounds of formula (I), (II), or (II-A): and pharmaceutically acceptable salts thereof, compositions comprising these compounds, and methods of using these compounds in a variety of applications, such as treatment or suppression of diseases associated with decreased mitochondrial function resulting in diminished ATP production and/or oxidative stress and/or lipid peroxidation.

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