251570-03-3

Basic information

• Product Name: (4-CHLORO-3-FLUORO-PHENYL)-ACETONITRILE
• Synonyms: 3-FLUORO-4-CHLOROBENZYL CYANIDE;3-FLUORO-4-CHLORO PHENYLACETONITRILE;3-Fluoro-4-Chloro Phenylacetonitrile 3-Fluoro-4-Chlorobenzyl Cyanide;4-CHLORO-3-FLUOROPHHENYLACETONITRILE;2-(4-chloro-3-fluorophenyl)acetonitrile;(4-CHLORO-3-FLUORO-PHENYL)-ACETONITRILE;4-CHLORO-3-FLUOROBENZYLCYANIDE
• CAS NO: 251570-03-3
• Molecular Formula: C₈H₅ClFN
• Molecular Weight: 169.58
• Product Categories: Nitrile;Fluorine series
• Mol File: 251570-03-3.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 253.425 °C at 760 mmHg
• Flash Point: 107.068 °C
• Appearance: /
• Density: 1.287 g/cm³
• Vapor Pressure: 0.0183mmHg at 25°C
• Refractive Index: 1.528
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: (4-CHLORO-3-FLUORO-PHENYL)-ACETONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: (4-CHLORO-3-FLUORO-PHENYL)-ACETONITRILE(251570-03-3)
• EPA Substance Registry System: (4-CHLORO-3-FLUORO-PHENYL)-ACETONITRILE(251570-03-3)

Safety Data

• Hazard Codes: T
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36/37/39
• RIDADR: 3276
• Hazardous Substances Data: 251570-03-3(Hazardous Substances Data)

Usage

Chemical Properties

Pale yellow liquid

InChI:InChI=1/C8H5ClFN/c9-7-2-1-6(3-4-11)5-8(7)10/h1-2,5H,3H2

Upstream product

• 206362-80-3 4-(bromomethyl)-1-chloro-2-fluorobenzene 
• 60811-18-9 2-chloro-5-bromofluorobenzene 
• 3264-82-2 nickel(II) acetylacetonate 
• 590-17-0 cyanomethyl bromide 
• 151-50-8 potassium cyanide 
• 140-53-4 p-chlorobenzyl cyanide 

Downstream Products

• 883500-51-4 2-(4-chloro-3-fluorophenyl)acetic acid 
• 1265476-80-9 1-(4-chloro-3-fluorophenyl)cyclopropanecarbonitrile 
• 1268444-83-2 1-(4-chloro-3-fluorophenyl)cyclopropanecarboxylic acid 
• 1268445-06-2 (4R)-1-{[1-(4-chloro-3-fluorophenyl)cyclopropyl]carbonyl}-4-{[2-chloro-4-(2,2,2-trifluoroethoxy)phenyl]sulfonyl}-N-(1-cyanocyclopropyl)-L-prolinamide 
• 1252641-41-0 (4R)-1-{[1-(4-chloro-3-fluorophenyl)cyclopropyl]carbonyl}-4-[(2-chlorophenyl)sulfonyl]-N-(1-cyanocyclopropyl)-L-prolinamide 
• 243853-08-9 2-(4-chloro-3-fluoro-phenyl)-ethylamine 
• 1095544-05-0 2-(4-chloro-3-fluorophenyl)-2-methylpropanenitrile 

Relevant articles and documents

IMIDAZOPYRIMIDINONES AND USES THEREOF

The present invention provides a compound of formula (I) or a pharmaceutically acceptable derivative, salt or prodrug thereof. The present invention further provides a method of treatment or prophylaxis of a viral infection in a subject comprising administering to said subject an effective amount of a compound of formula (I) or a pharmaceutically acceptable derivative, salt or prodrug thereof. Pharmaceutical compositions comprising a compound of formula (I) are also provided.

THIAZOPYRIMIDINONES AND USES THEREOF

The present invention provides a compound of formula (I) or a pharmaceutically acceptable derivative, salt or prodrug thereof. The present invention further provides a method of treatment or prophylaxis of a viral infection in a subject comprising adminis

Piperidones as tachykinin antagonists

The present invention relates to a compound of the formula:- or a pharmaceutically acceptable acid addition salt or solvate thereof, wherein R is C3-C7 cycloalkyl, (C3-C7 cycloalkyl)C1-C4 alkylene or benzyl;R1 is phenyl optionally substituted by 1 or 2 su