251349-54-9 Usage
Description
2-[(2S)-1-[(1,1-dimethylethoxy)carbonyl]2-pyrrolidinyl]-4-thiazolecarboxylic acid is a complex organic chemical compound characterized by a molecular formula of C15H21N3O4S. It features a pyrrolidine ring, a thiazole ring, and a carboxylic acid functional group, which contribute to its unique chemical properties and potential applications in the field of oncology. 2-[(2S)-1-[(1,1-diMethylethoxy)carbonyl]2-pyrrolidinyl]-4-thiazolecarboxylic acid functions as a potent inhibitor of Cdc7, a serine/threonine protein kinase that plays a crucial role in cell division, thereby exhibiting significant anti-cancer activity by impeding the proliferation of cancer cells.
Uses
Used in Cancer Therapy:
2-[(2S)-1-[(1,1-dimethylethoxy)carbonyl]2-pyrrolidinyl]-4-thiazolecarboxylic acid is used as an anti-cancer agent for its ability to inhibit the progression of cancer cells. It targets the Cdc7 protein kinase, which is essential for the initiation of DNA replication, thus preventing uncontrolled cell division characteristic of cancer.
Used in Pharmaceutical Research and Development:
In the pharmaceutical industry, 2-[(2S)-1-[(1,1-dimethylethoxy)carbonyl]2-pyrrolidinyl]-4-thiazolecarboxylic acid is utilized as a key compound in the development of novel cancer treatments. Its unique structure and mechanism of action offer new avenues for the creation of drugs with potential to overcome resistance and improve patient outcomes.
Used in Drug Synthesis:
2-[(2S)-1-[(1,1-dimethylethoxy)carbonyl]2-pyrrolidinyl]-4-thiazolecarboxylic acid serves as a building block in the synthesis of other pharmaceuticals, leveraging its chemical properties to create new molecules with potential therapeutic benefits.
Further research and clinical trials are necessary to fully explore the therapeutic potential of 2-[(2S)-1-[(1,1-dimethylethoxy)carbonyl]2-pyrrolidinyl]-4-thiazolecarboxylic acid, including its efficacy, safety, and optimal delivery methods in cancer treatment.
Check Digit Verification of cas no
The CAS Registry Mumber 251349-54-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,1,3,4 and 9 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 251349-54:
(8*2)+(7*5)+(6*1)+(5*3)+(4*4)+(3*9)+(2*5)+(1*4)=129
129 % 10 = 9
So 251349-54-9 is a valid CAS Registry Number.
251349-54-9Relevant articles and documents
HMG-COA REDUCTASE DEGRADATION INDUCING COMPOUND
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Paragraph 661; 668-670, (2021/10/11)
The present invention relates HMG-CoA reductase degradation inducing compounds. Specifically, the present invention relates a bifunctional compound in which a HMG-CoA reductase binding moiety and an E3 ubiquitin ligase-binding moiety are linked by a chemical linker. The present invention also relates a method for preparing the compounds, and a method for degradation of HMG-CoA reducatase using the compounds, as well as use for prevention or treatment of HMG-CoA reductase related diseases using the compounds.
MDM2 DEGRADERS AND USES THEREOF
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, (2021/09/26)
The present invention relates to compounds and methods useful for the modulation of mouse double minute 2 homolog ("MDM2") protein via ubiquitination and/or degradation by compounds according to the present invention.
BIFUNCTIONAL COMPOUNDS FOR DEGRADING BTK VIA UBIQUITIN PROTEOSOME PATHWAY
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, (2020/05/21)
The present invention relates to compounds useful for degrading BTK via a ubiquitin proteolytic pathway. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.
