24991-53-5

Basic information

• Product Name: H2N-PEG-NH2
• Synonyms: PEG-WM 6000;PEG-WM 10000;PEG-WM 2000;PEG-WM 20000;PEG-WM 3000;PEG-DIAMINE;O,O'-BIS(2-AMINOETHYL)POLYETHYLENE GLYCOL 10,000;O,O'-BIS(2-AMINOETHYL)POLYETHYLENE GLYCOL 10'000
• CAS NO: 24991-53-5
• Molecular Formula: C4H12N2O
• Molecular Weight: 104.15088
• EINECS: 939-622-0
• Product Categories: Polydispersed PEG;pegXlink;PEG
• Mol File: 24991-53-5.mol
• Article Data: 0

Chemical Properties

• Melting Point: 56-60°C
• Boiling Point: 241°C at 760mmHg
• Flash Point: >110℃
• Appearance: White to off-white/Granular Solid
• Density: 1.003g/cm³
• Storage Temp.: −20°C
• Solubility: Soluble in organic solvents.
• Water Solubility: It is soluble in organic solvents. It is insoluble in water.
• Sensitive: Air Sensitive
• CAS DataBase Reference: H2N-PEG-NH2(CAS DataBase Reference)
• NIST Chemistry Reference: H2N-PEG-NH2(24991-53-5)
• EPA Substance Registry System: H2N-PEG-NH2(24991-53-5)

Safety Data

• Hazard Codes: Xn
• Statements: 36/37/38-42/43-36/38
• Safety Statements: 22-24/25-45-36/37-26
• WGK Germany: 3
• F: 10-23
• Hazardous Substances Data: 24991-53-5(Hazardous Substances Data)

Usage

Description

H2N-PEG-NH2, also known as Poly(ethylene glycol) diamine (PEGD), is a non-toxic biopolymer derived from polyethylene glycol. It possesses properties such as biocompatibility, biodegradability, and reactivity with various functional groups like carboxylic acids, activated NHS esters, and carbonyls. H2N-PEG-NH2 is a monodisperse PEG linker containing two terminal amine moieties, which makes it a versatile molecule for various applications.
Chemical Properties:
H2N-PEG-NH2 appears as a white to slightly yellowish powder.

Uses

Used in Drug Delivery Systems:
H2N-PEG-NH2 is used as a polymer for preparing enzyme conjugates soluble in organic solvents, making it a promising drug carrier. It can be reacted with crosslinking agents to form a three-dimensional mesh that can be used in drug delivery systems, enhancing the bioavailability and therapeutic outcomes of various drugs.
Used in Biomedical Applications:
H2N-PEG-NH2 is used as a non-ionic surfactant for a variety of biological applications, including the creation of photodegradable poly(ethylene glycol)-based hydrogels. These hydrogels have potential applications in tissue engineering, wound healing, and controlled drug release.
Used in Chemical Synthesis:
H2N-PEG-NH2 is used as a monodisperse PEG linker containing two terminal amine moieties, which are reactive with various functional groups. This makes it a valuable building block for the synthesis of complex molecules and materials in the fields of pharmaceuticals, diagnostics, and materials science.
Used in Research and Development:
H2N-PEG-NH2 is used as a versatile molecule for research and development purposes, particularly in the fields of biochemistry, molecular biology, and drug discovery. Its unique properties and reactivity make it an attractive candidate for the development of new drugs, drug delivery systems, and diagnostic tools.