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  • 2486-80-8 Structure
  • Basic information

    1. Product Name: 4-AMINO-2-METHOXYBENZOIC ACID
    2. Synonyms: 4-AMINO-2-METHOXYBENZENECARBOXYLIC ACID;4-AMINO-2-METHOXYBENZOIC ACID;2-METHOXY-4-AMINO-BENZOIC ACID;4-amino-o-anisic acid;4-azanyl-2-methoxy-benzoic acid;NSC 208766;4-Amino-o-anisic acid, 4-Carboxy-3-methoxyaniline;4-Amino-2-methoxybenzoic acid 97%
    3. CAS NO:2486-80-8
    4. Molecular Formula: C8H9NO3
    5. Molecular Weight: 167.16
    6. EINECS: 219-632-5
    7. Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Aromatics Compounds;Aromatics;Aromatic Amino Acids;Peptide Synthesis;Unnatural Amino Acid Derivatives
    8. Mol File: 2486-80-8.mol
    9. Article Data: 10
  • Chemical Properties

    1. Melting Point: 149-153 °C(lit.)
    2. Boiling Point: 365.9 °C at 760 mmHg
    3. Flash Point: 175.1 °C
    4. Appearance: Yellow crystalline solid
    5. Density: 1.303 g/cm3
    6. Vapor Pressure: 5.37E-06mmHg at 25°C
    7. Refractive Index: 1.603
    8. Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
    9. Solubility: Chloroform, Dichloromethane, Methanol
    10. PKA: 4.75±0.10(Predicted)
    11. CAS DataBase Reference: 4-AMINO-2-METHOXYBENZOIC ACID(CAS DataBase Reference)
    12. NIST Chemistry Reference: 4-AMINO-2-METHOXYBENZOIC ACID(2486-80-8)
    13. EPA Substance Registry System: 4-AMINO-2-METHOXYBENZOIC ACID(2486-80-8)
  • Safety Data

    1. Hazard Codes: Xi
    2. Statements: 36/37/38
    3. Safety Statements: 26-36
    4. WGK Germany: 3
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 2486-80-8(Hazardous Substances Data)

2486-80-8 Usage

Description

4-Amino-2-methoxybenzoic acid, with the CAS number 2486-80-8, is a yellow crystalline solid that serves as a valuable compound in the realm of organic synthesis. Its unique chemical structure, featuring an amino group at the 4-position and a methoxy group at the 2-position on a benzoic acid backbone, endows it with versatile reactivity and potential applications across various industries.

Uses

Used in Pharmaceutical Industry:
4-Amino-2-methoxybenzoic acid is used as an intermediate in the synthesis of various pharmaceutical compounds. Its chemical structure allows for further functionalization and modification, making it a key building block in the development of new drugs with potential therapeutic applications.
Used in Chemical Synthesis:
In the field of chemical synthesis, 4-Amino-2-methoxybenzoic acid is utilized as a starting material for the production of a wide range of organic compounds. Its reactivity and functional groups enable the creation of diverse chemical entities, including dyes, pigments, and other specialty chemicals.
Used in Material Science:
4-Amino-2-methoxybenzoic acid finds application in material science as a component in the development of novel materials with specific properties. Its incorporation into polymers or other materials can lead to enhanced performance characteristics, such as improved stability, reactivity, or optical properties.
Used in Research and Development:
As a compound with unique chemical properties, 4-Amino-2-methoxybenzoic acid is employed in research and development for the exploration of new chemical reactions, mechanisms, and applications. Its use in this context aids in advancing the understanding of organic chemistry and the discovery of new synthetic pathways and methodologies.

Check Digit Verification of cas no

The CAS Registry Mumber 2486-80-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,4,8 and 6 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 2486-80:
(6*2)+(5*4)+(4*8)+(3*6)+(2*8)+(1*0)=98
98 % 10 = 8
So 2486-80-8 is a valid CAS Registry Number.
InChI:InChI=1/C8H9NO3/c1-12-7-4-5(9)2-3-6(7)8(10)11/h2-4H,9H2,1H3,(H,10,11)

2486-80-8 Well-known Company Product Price

  • Brand
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  • Alfa Aesar

  • (H27419)  4-Amino-2-methoxybenzoic acid, 97%   

  • 2486-80-8

  • 5g

  • 217.0CNY

  • Detail
  • Alfa Aesar

  • (H27419)  4-Amino-2-methoxybenzoic acid, 97%   

  • 2486-80-8

  • 25g

  • 520.0CNY

  • Detail
  • Aldrich

  • (647624)  4-Amino-2-methoxybenzoicacid  97%

  • 2486-80-8

  • 647624-5G

  • 175.50CNY

  • Detail
  • Aldrich

  • (647624)  4-Amino-2-methoxybenzoicacid  97%

  • 2486-80-8

  • 647624-25G

  • 524.16CNY

  • Detail

2486-80-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-AMINO-2-METHOXYBENZOIC ACID

1.2 Other means of identification

Product number -
Other names 4-amino-2-methoxybenzenecarboxylic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:2486-80-8 SDS

2486-80-8Relevant articles and documents

Chlorination Reaction of Aromatic Compounds and Unsaturated Carbon-Carbon Bonds with Chlorine on Demand

Liu, Feng,Wu, Na,Cheng, Xu

supporting information, p. 3015 - 3020 (2021/05/05)

Chlorination with chlorine is straightforward, highly reactive, and versatile, but it has significant limitations. In this Letter, we introduce a protocol that could combine the efficiency of electrochemical transformation and the high reactivity of chlorine. By utilizing Cl3CCN as the chloride source, donating up to all three chloride atom, the reaction could generate and consume the chlorine in situ on demand to achieve the chlorination of aromatic compounds and electrodeficient alkenes.

Salicylic-acid derivatives as antennae for ratiometric luminescent probes based on lanthanide complexes

Terai, Takuya,Ito, Hiroki,Kikuchi, Kazuya,Nagano, Tetsuo

, p. 7377 - 7381 (2012/07/30)

Long-lived ratiometric sensors: Luminescent lanthanide complexes are widely used in time-resolved assays of biomolecules, but most of the sensors with these complexes rely on single-point intensity measurements. Herein, we introduce a simple strategy to create ratiometric probes by using salicylic-acid derivatives as the antenna moiety of Tb3+ complexes. As an example, a probe for alkaline phosphatase (ALP) was developed (see scheme). Copyright

Indole-type derivatives as inhibitors of p38 kinase

-

Page/Page column 69-70, (2008/06/13)

The invention is directed to methods to inhibit p38-α kinase using compounds comprising a phenyl or thienyl coupled through a piperidine or piperazine nucleus to an indole residue wherein the indole residue mandatorily has a substituent on the ring nitrogen which is an amino or substituted amino group.

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