2439-55-6

Basic information

• Product Name: N-METHYL-N-OCTADECYLAMINE
• Synonyms: n-methyloctadecanamine;n-methyl-octadecylamin;N-Stearyl-N-methylamine;Octadecylamine, N-methyl-;Octadecylmethylamine;AURORA KA-7764;N-Methyloctadecylamine,96%;N-methyloctadecan-1-amine
• CAS NO: 2439-55-6
• Molecular Formula: C₁₉H₄₁N
• Molecular Weight: 283.54
• EINECS: 219-463-7
• Mol File: 2439-55-6.mol
• Article Data: 3

Chemical Properties

• Melting Point: 42-46 °C(lit.)
• Boiling Point: 346.08°C (estimate)
• Flash Point: >230 °F
• Appearance: /
• Density: 0.7953 (estimate)
• Vapor Pressure: 0.000151mmHg at 25°C
• Refractive Index: 1.4528 (estimate)
• Solubility: soluble in Methanol
• PKA: 10.78±0.10(Predicted)
• BRN: 1758431
• CAS DataBase Reference: N-METHYL-N-OCTADECYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: N-METHYL-N-OCTADECYLAMINE(2439-55-6)
• EPA Substance Registry System: N-METHYL-N-OCTADECYLAMINE(2439-55-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• WGK Germany: 3
• RTECS: RG4460000
• F: 10-34
• Hazardous Substances Data: 2439-55-6(Hazardous Substances Data)

Usage

Description

N-METHYL-N-OCTADECYLAMINE, also known as N-Methyloctadecylamine, is an aliphatic amine molecule characterized by its long hydrocarbon chain and amine functional group. It is known for its ability to interact with various substances, particularly in the context of extraction processes.

Uses

Used in Pharmaceutical Industry:
N-METHYL-N-OCTADECYLAMINE is used as an extraction agent for heparin, a highly sulfated glycosaminoglycan with significant anticoagulant properties. Its aliphatic amine structure allows it to effectively bind and separate heparin from other components, facilitating the purification process and ensuring the quality of the final product.

InChI:InChI=1/C19H41N/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-2/h20H,3-19H2,1-2H3

Upstream product

• 112-92-5 1-octadecanol 
• 74-89-5 methylamine 
• 3386-33-2 1-chlorooctadecane 
• 110-68-9 N-n-butyl-N-methylamine 
• 100515-11-5 3-(Methyl-octadecyl-amino)-propionamide 
• 100515-09-1 3-(Methyl-octadecyl-amino)-propionic acid methyl ester 
• 20198-92-9 N-methylstearylamide 

Downstream Products

• 63266-78-4 N-Methyl-2-{2-[(methyl-octadecyl-carbamoyl)-methoxy]-phenoxy}-N-octadecyl-acetamide 
• 50671-12-0 4-(N-Methyl-N-octadecylamino)-3-nitrobenzolsulfanilid 
• 56823-93-9 N-Methyl-N-n-octadecyl-(5-tert.-butyl-2,3-dimethyl-4-hydroxyphenyl)acetamid 
• 110-68-9 N-n-butyl-N-methylamine 
• 100515-09-1 3-(Methyl-octadecyl-amino)-propionic acid methyl ester 
• 100515-11-5 3-(Methyl-octadecyl-amino)-propionamide 
• 74109-27-6 C₂₆H₄₅N₃O₂ 
• 137482-77-0 [4-Chloro-6-(4-diethylamino-phenyl)-[1,3,5]triazin-2-yl]-methyl-octadecyl-amine 
• 95335-61-8 C₅₀H₈₄N₆O₂ 
• 55698-98-1 N-Methyl-N-n-octadecyl-4-tert.-butyl-2,6-dimethyl-3-hydroxyphenylacetamide 

Relevant articles and documents

Photochemical Cleavage of Benzylic C-N Bond to Release Amines

The 3-(diethylamino)benzyl (DEABn) group has been studied for releasing primary, secondary, and tertiary amines by direct photochemical breaking of the benzylic C-N bond. While photochemical release of primary and secondary amines provides high yields in

Kinetics of Reversible Endothermic Elimination Reactions: β-Amino Carboxylic Esters and Amides

The kinetics of the elimination reactions of substituted β-amino carboxylic esters and amides, to give amines and the α,β-unsaturated esters and amides, have been studied in several model systems.The reaction was studied by trapping the olefin formed with another nucleophile capable of competing with the amine formed by elimination.The rate constant for elimination of methyl 3-(N-methyl-N-butylamino)propionate, in methanol at room temperature, is 1.8E-6 s-1.The corresponding amide has an elimination rate constant 8.8E-8 s-1.Rate constants for the forward reaction were also measured and combined with the reversion rate constants to yield equilibrium constants for the same two systems.The equilibrium constants for the methyl esters is 2.0E4 L mol-1 and for the amides is 7.3E3 L mol-1.These were confirmed by measurement of the equilibrium concentrations of olefins by 1H NMR spectroscopy.