23628-31-1

Basic information

• Product Name: 6-Aminopyridine-2-carboxylic acid
• Synonyms: 6-aMinopyridine-2-carbo×ylic acid;6-Aminopicolinic acid, 2-Amino-6-carboxypyridine;6-Aminopyridine-2-carboxylicacid,95%;6-Aminopyridine-2-carboxylic acid≥ 99% (HPLC);2-PYRIDINECARBOXYLIC ACID, 6-AMINO-;2-AMINOPYRIDINE-6-CARBOXYLIC ACID;6-AMINOPICOLINIC ACID;6-AMINOPYRIDINE-2-CARBOXYLIC ACID
• CAS NO: 23628-31-1
• Molecular Formula: C₆H₆N₂O₂
• Molecular Weight: 138.12
• EINECS: 1308068-626-2
• Product Categories: NULL;Heterocycle-Pyridine series;AMINOACID;Amines;blocks;Carboxes;Pyridines;Pyridine;pharmacetical;Pyridine series;Carboxylic Acids;Organic acids;Carboxylic Acids
• Mol File: 23628-31-1.mol
• Article Data: 9

Chemical Properties

• Melting Point: 320°C
• Boiling Point: 387.8 °C at 760 mmHg
• Flash Point: 188.3 °C
• Appearance: light yellow crystals
• Density: 1.417 g/cm³
• Vapor Pressure: 1.05E-06mmHg at 25°C
• Refractive Index: 1.649
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 4.49±0.10(Predicted)
• Water Solubility: Soluble in hot water.
• CAS DataBase Reference: 6-Aminopyridine-2-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Aminopyridine-2-carboxylic acid(23628-31-1)
• EPA Substance Registry System: 6-Aminopyridine-2-carboxylic acid(23628-31-1)

Safety Data

• Hazard Codes: Xi,T,Xn
• Statements: 36/37/38-23/24/25-36-22
• Safety Statements: 26-36/37/39-45
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 23628-31-1(Hazardous Substances Data)

Usage

Description

6-Aminopyridine-2-carboxylic acid is an organic compound with the chemical formula C6H6N2O2. It is a light yellow crystalline substance that serves as a crucial reagent in the pharmaceutical industry and is also utilized in the synthesis of polyamides.

Uses

Used in Pharmaceutical Industry:
6-Aminopyridine-2-carboxylic acid is used as a reagent for the preparation of pharmaceuticals, specifically ghrelin receptor antagonists. These antagonists play a significant role in the treatment of various medical conditions, including obesity and other metabolic disorders, by targeting and blocking the ghrelin receptor.
Used in Polyamide Synthesis:
6-Aminopyridine-2-carboxylic acid is also employed in the production of polyamides, which are a class of polymers with diverse applications. These polymers are known for their strength, durability, and resistance to heat and chemicals, making them suitable for use in the manufacturing of textiles, plastics, and other industrial materials.

InChI:InChI=1/C6H6N2O2/c7-5-3-1-2-4(8-5)6(9)10/h1-3H,(H2,7,8)(H,9,10)

Upstream product

• 21190-87-4 6-bromo-pyridine-2-carboxylic acid 
• 13538-41-5 6-aminopyridine-2-carboxamide 
• 5327-33-3 2-acetylamino-6-methylpyridine 
• 1824-81-3 2-Amino-6-methylpyridine 
• 26893-72-1 6-acetamido-picolinic acid 
• 4684-94-0 6-chloropicolinic acid 

Downstream Products

• 258497-48-2 methyl 6-tert-butoxycarbonylamino-2-pyridinecarboxylate 
• 937-19-9 5-cyano-1H-pyrrole-2-carboxylic acid methyl ester 
• 1187317-72-1 N-methyl-[4-(5-oxo-4,5-dihydro-3H-1,4,8b-triazaacenaphthylen-2-yl)phenyl]methanamine trifluoroacetate 
• 1187318-35-9 4-(2,4-dimethoxybenzyl)-2-{4-[(methylamino)methyl]phenyl}-3,4-dihydro-5H-1,4,8b-triazaacenaphthylen-5-one 
• 1187318-33-7 4-[4-(2,4-dimethoxybenzyl)-5-oxo-4,5-dihydro-3H-1,4,8b-triazaacenaphthylen-2-yl]benzonitrile 
• 1187318-34-8 4-[4-(2,4-dimethoxybenzyl)-5-oxo-4,5-dihydro-3H-1,4,8b-triazaacenaphthylen-2-yl]benzaldehyde 
• 1187318-25-7 methyl 2-(4-cyanophenyl)-3-[(Z)-2-ethoxyvinyl]imidazo[1,2-a]pyridine-5-carboxylate 
• 1187318-32-6 methyl 2-(4-cyanophenyl)-3-formylimidazo[1,2-a]pyridine-5-carboxylate 
• 1187318-24-6 methyl 3-bromo-2-(4-cyanophenyl)imidazo[1,2-a]pyridine-5-carboxylate 
• 1187318-23-5 methyl 2-(4-cyanophenyl)imidazo[1,2-a]pyridine-5-carboxylate 
• 332884-35-2 2-aminopyridine-6-carbaldehyde 
• 203321-83-9 tert-butyl 6-(hydroxymethyl)-2-pyridinylcarbamate 

Relevant articles and documents

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Convenient synthesis of aminopyridinecarboxylic acids

6-(Alkylamino)pyridine-2-carboxylic acids and 5-(alkylamino)pyridine-3- carboxylic acids were conveniently synthesized from dibromopyridine in satisfactory yields.

BENZISOXAZOLE COMPOUND

Disclosed is a compound represented by the general formula (I) or a salt thereof: wherein any one of R1, R2 and R3 represents a group represented by the formula: -(CH2)m-NR11R12 (wherein m is 1 or 2; and R11 and R12 independently represent a hydrogen atom or a C1-6 alkyl group or may, together with a nitrogen atom to which R11 and R12 are bound, form a 4- or 5-membered cyclic group); the remaining two or R1, R2 and R3 independently represent a group represented by the formula: -(O)n-R21 (wherein n is 0 or 1; and R21 represents a hydrogen atom, a C1-6 alkyl group, a C2-6 alkenyl group, a C2-6 alkynyl group, or the like); and R4 represents a C1-6 alkyl group which may have a substituent or the like.