23043-41-6

Basic information

• Product Name: 1-methylacridine
• Synonyms: 1-methylacridine
• CAS NO: 23043-41-6
• Molecular Formula: C₁₄H₁₁N
• Molecular Weight: 193.24384
• EINECS: 245-395-2
• Mol File: 23043-41-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 361.9 °C at 760 mmHg
• Flash Point: 160 °C
• Appearance: /
• Density: 1.155 g/cm³
• Vapor Pressure: 4.19E-05mmHg at 25°C
• Refractive Index: 1.703
• CAS DataBase Reference: 1-methylacridine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methylacridine(23043-41-6)
• EPA Substance Registry System: 1-methylacridine(23043-41-6)

Safety Data

• Hazardous Substances Data: 23043-41-6(Hazardous Substances Data)

Usage

Description

1-methylacridine is a chemical compound with the molecular formula C13H11N. It is a derivative of acridine, a heterocyclic organic compound, known for its applications in organic synthesis, production of dyes, pharmaceuticals, and agrochemicals. 1-methylacridine also exhibits fluorescence properties, making it a valuable fluorescent tag in biological and chemical research. Furthermore, 1-methylacridine has been investigated for its potential anti-cancer and anti-microbial activities. However, it is essential to handle and use 1-methylacridine with caution due to its irritant properties and potential health risks if not properly managed.

Uses

Used in Organic Synthesis:
1-methylacridine is used as a building block in organic synthesis for the creation of various chemical compounds and materials.
Used in Dye Production:
1-methylacridine is used as a precursor in the production of dyes, contributing to the coloration and properties of these products.
Used in Pharmaceutical Industry:
1-methylacridine is used as a starting material or intermediate in the development of pharmaceuticals, potentially leading to new medications.
Used in Agrochemicals:
1-methylacridine is utilized in the formulation of agrochemicals, which are essential for crop protection and enhancement of agricultural yields.
Used as a Fluorescent Tag in Research:
1-methylacridine is used as a fluorescent tag in biological and chemical research, aiding in the visualization and tracking of molecules and cellular processes.
Used in Anti-Cancer Research:
1-methylacridine is investigated for its potential anti-cancer activities, with the aim of developing new therapeutic agents for cancer treatment.
Used in Anti-Microbial Research:
1-methylacridine is explored for its potential anti-microbial properties, which could lead to the development of new antimicrobial agents to combat resistant infections.

InChI:InChI=1/C14H11N/c1-10-5-4-8-14-12(10)9-11-6-2-3-7-13(11)15-14/h2-9H,1H3

Upstream product

• 586-96-9 Nitrosobenzene 
• 529-20-4 2-methylphenyl aldehyde 
• 62-53-3 aniline 
• 622-37-7 Phenyl azide 
• 65753-71-1 1-methylacridin-9(10H)-one 
• 115957-39-6 1-methyl-9,10-dihydro-acridine 

Downstream Products

• 113139-09-6 N'-(4-acridinylmethylidene)-4-dimethylaminoaniline N'-oxide 

Relevant articles and documents

Rh(III)-catalyzed synthesis of unsymmetrical acridines from aldehydes and azides using transient directing strategy in biomass-derived γ-valerolactone

An Rh(III)-catalyzed synthesis of unsymmetrical acridines from aldehydes and azides through bilateral cyclization process in biomass-derived γ-valerolactone has been developed. The in situ-generated imino directing group (DG) from aldehyde and catalytic a

N-arylation of isatins

A process for the N-arylation of isatins with organo bismuth reagents is disclosed.