23028-17-3

Basic information

• Product Name: 3-(3,4-dihydroxyphenyl)-2-hydroxy-propanoic acid
• Synonyms: 3-(3,4-dihydroxyphenyl)-2-hydroxy-propanoic acid;3-(3,4-Dihydroxyphenyl)lactic acid;3,4-dihydroxyphenyllactic acid;3,4-DIHYDROXYPHENYLLACTIC ACID SODIUM SALT 90%;2-Hydroxy-3-(3,4-dihydroxyphenyl)propanoic acid;2-Hydroxy-3-(3,4-dihydroxyphenyl)propionic acid;3-(3,4-Dihydroxyphenyl)-2-hydroxypropionic acid;α,3,4-Trihydroxybenzenepropanoic acid
• CAS NO: 23028-17-3
• Molecular Formula: C₉H₁₀O₅
• Molecular Weight: 198.05
• Mol File: 23028-17-3.mol
• Article Data: 26

Chemical Properties

• Boiling Point: 481.469 °C at 760 mmHg
• Flash Point: 259.091 °C
• Appearance: /
• Density: 1.546±0.06 g/cm3 (20 ºC 760 Torr)
• Vapor Pressure: 4.91E-10mmHg at 25°C
• Refractive Index: 1.649
• PKA: 3.82±0.10(Predicted)
• CAS DataBase Reference: 3-(3,4-dihydroxyphenyl)-2-hydroxy-propanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3,4-dihydroxyphenyl)-2-hydroxy-propanoic acid(23028-17-3)
• EPA Substance Registry System: 3-(3,4-dihydroxyphenyl)-2-hydroxy-propanoic acid(23028-17-3)

Safety Data

• Hazardous Substances Data: 23028-17-3(Hazardous Substances Data)

Usage

Description

3-(3,4-dihydroxyphenyl)-2-hydroxy-propanoic acid, also known as dihydroxyphenyllactic acid, is a phenolic acid derivative of lactic acid with the molecular formula C9H10O5. It is a colorless crystalline solid that is naturally present in various plant sources such as fruits, vegetables, and nuts. 3-(3,4-dihydroxyphenyl)-2-hydroxy-propanoic acid is recognized for its antioxidant properties and has been the subject of research for its potential health benefits, which include anti-inflammatory and neuroprotective effects. Its occurrence in dietary sources and its biological activities make 3-(3,4-dihydroxyphenyl)-2-hydroxy-propanoic acid a significant molecule of interest in the realms of nutrition and medicine.

Uses

Used in Pharmaceutical Industry:
3-(3,4-dihydroxyphenyl)-2-hydroxy-propanoic acid is used as a pharmaceutical agent for its potential health benefits, leveraging its antioxidant properties to contribute to anti-inflammatory and neuroprotective effects. Its presence in natural dietary sources underscores its potential as a therapeutic compound.
Used in Nutritional Supplements:
In the nutritional supplement industry, 3-(3,4-dihydroxyphenyl)-2-hydroxy-propanoic acid is utilized as an ingredient to enhance the antioxidant capacity of supplements, aiming to support overall health and well-being by providing additional anti-inflammatory and neuroprotective benefits.
Used in Functional Foods:
3-(3,4-dihydroxyphenyl)-2-hydroxy-propanoic acid is employed as an additive in functional foods to capitalize on its health-promoting properties. Its incorporation into food products can offer consumers the benefits of its antioxidant, anti-inflammatory, and neuroprotective effects, contributing to a more health-conscious diet.
Used in Cosmetics:
In the cosmetics industry, 3-(3,4-dihydroxyphenyl)-2-hydroxy-propanoic acid is used as an active ingredient for its antioxidant and potentially anti-aging properties. It may be incorporated into skincare products to protect the skin from oxidative stress and support skin health.
Used in Agricultural Products:
3-(3,4-dihydroxyphenyl)-2-hydroxy-propanoic acid may also find use in agricultural applications, potentially serving as a natural antioxidant to extend the shelf life of fruits and vegetables, thereby reducing spoilage and waste.

InChI:InChI=1/C9H10O5/c1-9(14,8(12)13)5-2-3-6(10)7(11)4-5/h2-4,10-11,14H,1H3,(H,12,13)

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Downstream Products

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• 179462-77-2 (E)-3-(3,4-Bis-allyloxy-phenyl)-acrylic acid (R)-1-allyloxycarbonyl-2-(3,4-bis-allyloxy-phenyl)-ethyl ester 

Relevant articles and documents

Salvianolic acids T and U: A pair of atropisomeric trimeric caffeic acids derivatives from root of Salvia miltiorrhiza

Two new trimeric caffeic acids, named salvianolic acids T and U (1 and 2), were isolated from the underground part of Salvia miltiorrhiza. Their structures, consisting of three caffeic acid units, were determined based on extensive 1D- and 2D-spectroscopic analyses and electronic circular dichroism (ECD) calculations.

Hydrolysis of Rosmarinic Acid from Rosemary Extract with Esterases and Lactobacillus johnsonii in Vitro and in a Gastrointestinal Model

Rosmarinic acid (RA) was identified as one of the main components of rosemary extracts and has been ascribed to a number of health benefits. Several studies suggested that after ingestion, RA is metabolized by gut microflora into caffeic acid and derivati

Salvianolic acid L, a potent phenolic antioxidant from Salvia officinalis

Salvianolic acid L, a rosmarinic acid dimer, was isolated from Salvia officinalis and identified as 7,8-dihydroxy-2-(3,4-dihydroxyphenyl)-1,2-dihydronaphthalene-1,3-dicarboxylic acid di(1-carboxy-2-(3,4-dihydroxyphenyl))ethyl ester. Two novel hydrolytic products 7,8-dihydroxy-2-(3,4-dihydroxyphenyl)-1,2-dihydronaphthalene-1,3-dicarboxylic acid and the corresponding 3-monoester were also isolated and characterized. Salvianolic acid L showed strong free radical scavenging activities for DPPH and superoxide anion radicals.

New phenolic glycosides from Anemone chinensis Bunge and their antioxidant activity

ABATRACT: Nine compounds, five phenolic glycosides (1, 2, 4–6), three phenylpropanoids (7–9), and a furanone glycoside (3), were isolated from aqueous soluble extract of the dried roots of Anemone chinensis Bunge. The structures of new compounds (1–4) were elucidated by comprehensive spectroscopic data analysis as well as chemical evidence. Pulsatillanin A (1) demonstrated significant antioxidant effects through scavenging free radical in DPPH assay, and relieved the oxidative stress in LPS-induced RAW 264.7 cells by reducing ROS production, enhancing antioxidant enzyme SOD activity, replenishing depleted GSH in a dose-dependent manner. Western blot analysis revealed that 1 showed antioxidant activity via activating Nrf2 signaling pathway.