2295-06-9 Usage
Description
1,3-Bis(chlorodimethylsilyl)propane, with the molecular formula C7H18Cl2Si2, is a colorless liquid chemical compound. It is characterized by its high reactivity due to the presence of chlorodimethylsilyl groups, which readily participate in substitution reactions with nucleophiles. This property makes it a valuable reagent in organic synthesis, especially for the preparation of silicon-containing compounds and polymers. Additionally, it serves as a protective group for alcohols and amines in synthetic reactions, highlighting its versatility in chemical processes.
Uses
Used in Organic Synthesis:
1,3-Bis(chlorodimethylsilyl)propane is used as a reagent for the preparation of silicon-containing compounds and polymers, leveraging its reactive chlorodimethylsilyl groups to facilitate substitution reactions with nucleophiles.
Used as a Protective Group in Synthetic Reactions:
In the chemical synthesis industry, 1,3-Bis(chlorodimethylsilyl)propane is employed as a protective group for alcohols and amines. This application is crucial for preventing unwanted side reactions during the synthesis process, thereby enhancing the yield and purity of the desired products.
Safety Considerations:
Given the compound's reactive nature and potential for hazardous exposure, it is imperative to follow appropriate safety measures when handling 1,3-Bis(chlorodimethylsilyl)propane. This includes the use of personal protective equipment, working in well-ventilated areas, and adhering to established safety protocols to minimize risks associated with its use.
Check Digit Verification of cas no
The CAS Registry Mumber 2295-06-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,2,9 and 5 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 2295-06:
(6*2)+(5*2)+(4*9)+(3*5)+(2*0)+(1*6)=79
79 % 10 = 9
So 2295-06-9 is a valid CAS Registry Number.
InChI:InChI=1/C7H18Cl2Si2/c1-10(2,8)6-5-7-11(3,4)9/h5-7H2,1-4H3
2295-06-9Relevant articles and documents
Anionic Ring-opening Polymerization of 1,1,2,2-Tetramethyl-1,2-disilacyclopentane
Suzuki, Masato,Obayashi, Tatsuhiko,Saegusa, Takeo
, p. 717 - 718 (1993)
Ring-opening polymerization of 1,1,2,2-tetramethyl-1,2-disilacyclopentane took place with the aid of Me3SiM (M = Na, K, Li) as initiator.
Sila-pharmaca. XXVI. Preparation and properties of silicon compounds with potential curare-like activity, III
Tacke,Linoh,Attar Bashi,et al.
, p. 1461 - 1471 (1982)
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Dramatic enhancement of reactivity of organosilicon compounds induced by complexation of bis(allyl)silanes with fluoride ion
Shibato, Atsushi,Itagaki, Yoshifumi,Tayama, Eiji,Hokke, Yasutoshi,Asao, Naoki,Maruoka, Keiji
, p. 5373 - 5382 (2007/10/03)
New type of fluoride ion catalyzed allylation agent (1a, 1b), allenylation agent (9, 10), and alkynylation agent (17) can be successfully utilized for various carbonyl substrates. The rate acceleration is ascribable to the shift of equilibrium to the chel