22609-73-0

Basic information

• Product Name: Niludipine
• Synonyms: NILUDIPINE;(2-propoxyethyl)ester;5-pyridinedicarboxylicacid,1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-bis;bay-a7168;bis(2-propoxyethyl)1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedi;niludipin;Bis(2-propoxyethyl) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate;1,4-Dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylic acid bis(2-propoxyethyl) ester
• CAS NO: 22609-73-0
• Molecular Formula: C₂₅H₃₄N₂O₈
• Molecular Weight: 490.55
• EINECS: 245-120-6
• Mol File: 22609-73-0.mol
• Article Data: 1

Chemical Properties

• Melting Point: 83-86 °C
• Boiling Point: 585.03°C (rough estimate)
• Flash Point: 315.102 °C
• Appearance: /
• Density: 1.2745 (rough estimate)
• Vapor Pressure: 3.1E-14mmHg at 25°C
• Refractive Index: 1.5500 (estimate)
• PKA: 2.60±0.70(Predicted)
• CAS DataBase Reference: Niludipine(CAS DataBase Reference)
• NIST Chemistry Reference: Niludipine(22609-73-0)
• EPA Substance Registry System: Niludipine(22609-73-0)

Safety Data

• Hazardous Substances Data: 22609-73-0(Hazardous Substances Data)

Usage

General Description

Niludipine is a calcium channel blocker used in the treatment of hypertension and angina. It works by relaxing the blood vessels, which allows for easier blood flow and lowers blood pressure. This medication is available in tablet form and is usually taken once a day. Niludipine is well tolerated by most patients, with the most common side effects being headache and dizziness. It should be used with caution in patients with liver or kidney disease, and dosage adjustments may be necessary in these cases. Overall, Niludipine is an effective and well-tolerated medication for the management of high blood pressure and angina.

InChI:InChI=1/C25H34N2O8/c1-5-10-32-12-14-34-24(28)21-17(3)26-18(4)22(25(29)35-15-13-33-11-6-2)23(21)19-8-7-9-20(16-19)27(30)31/h7-9,16,23,26H,5-6,10-15H2,1-4H3

Downstream Products

• 88443-04-3 2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid bis(2-propoxyethyl) ester 

Relevant articles and documents

The influence of the ester function on the vasodilating activity of 1,4-dihydro-2,6-dimethyl-4-nitrophenyl-pyridine-3,5-dicarboxylates

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