22237-13-4 Usage
Description
4-Ethoxyphenylboronic acid is an organic compound that serves as a versatile reagent and building block in organic synthesis. It is a white crystalline powder with chemical properties that make it suitable for various applications in the pharmaceutical and chemical industries.
Uses
Used in Pharmaceutical Industry:
4-Ethoxyphenylboronic acid is used as a reactant in the synthesis of biologically active molecules for the treatment of various diseases. It is involved in the production of novel modulators of survival motor neuron protein for the treatment of spinal muscular atrophy.
Used in Chemical Industry:
4-Ethoxyphenylboronic acid is used as a reactant in Suzuki cross-coupling reactions, a widely used method in organic synthesis for the formation of carbon-carbon bonds. This reaction is employed in the synthesis of various compounds, including:
Amino-trimethoxyphenyl-aryl thiazoles, which are used as microtubule inhibitors and antitumor agents.
Bicyclic hydroxyphenyl methanone derivatives, which are used as hydroxysteroid dehydrogenase inhibitors.
Dual immunosuppressive and anti-inflammatory agents.
Antiproliferatives via Suzuki cross-coupling / amination reactions.
Overall, 4-ethoxyphenylboronic acid is a valuable compound in the fields of pharmaceuticals and organic synthesis, contributing to the development of new drugs and chemical compounds with potential therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 22237-13-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,2,3 and 7 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 22237-13:
(7*2)+(6*2)+(5*2)+(4*3)+(3*7)+(2*1)+(1*3)=74
74 % 10 = 4
So 22237-13-4 is a valid CAS Registry Number.
22237-13-4Relevant articles and documents
Brominated thiophenes as precursors in the preparation of brominated and arylated anthraquinones
Thiemann, Thies,Tanaka, Yasuko,Iniesta, Jesus
experimental part, p. 1013 - 1031 (2009/10/10)
Brominated anthraquinones can be synthesized directly from bromothiophenes when these are reacted with 1,4-naphthoquinones in the presence of meta-chloroperoxybenzoic acid. The bromoanthraquinones are versatile building blocks in the preparation of arylated anthraquinones and of extended π-systems with interspersed anthraquinone units.
Small molecule thienopyrimidine-based protein tyrosine kinase inhibitors
-
Page/Page column 41, (2010/02/15)
Various thienopyrimidine-based analog compounds are able to selectively inhibit the Src family of tyrosine kinases. These compounds are useful in the treatment of various diseases including hyperproliferative diseases, hematologic diseases, osteoporosis, neurological diseases, autoimmune diseases, allergic/immunological diseases, or viral infections.
Synthesis and Properties of Liquid Crystalline 4,4 -Dialkoxy-2'-Methyl-p-Terphenyls
Yu, Z. N.,Tu, H. L.,Wan, X. H.,Chen, X. F.,Zhou, Q. F.
, p. 41 - 56 (2007/10/03)
A new series of laterally substituted terphenyl compounds, 4,4 -dialkoxy-2'-methyl-p-terphenyls (n = 1-12), were synthesized. Their liquid crystallinities were characterized by means of polarizing optical microscopy (POM), differential scanning calorimetry (DSC), and X-ray difraction (XRD). The influence of the length of the terminal alkoxy groups on the liquid crystalline behavior was investigated. It was found that the compounds with shorter end chains (n a smectic A mesophase is exhibited for those with longer end chains (9 = n = 12).
