220798-52-7

Basic information

• Product Name: 3-Bromomethylbenzenesulfonamide
• Synonyms: 3-Bromomethylbenzenesulfonamide;3-(broMoMethyl)benzene-1-sulfonaMide
• CAS NO: 220798-52-7
• Molecular Formula: C₇H₈BrNO₂S
• Molecular Weight: 250.115
• Mol File: 220798-52-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 402°C at 760 mmHg
• Flash Point: 196.9°C
• Appearance: /
• Density: 1.691
• Vapor Pressure: 1.13E-06mmHg at 25°C
• Refractive Index: 1.614
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 3-Bromomethylbenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Bromomethylbenzenesulfonamide(220798-52-7)
• EPA Substance Registry System: 3-Bromomethylbenzenesulfonamide(220798-52-7)

Safety Data

• Hazardous Substances Data: 220798-52-7(Hazardous Substances Data)

Usage

Description

3-Bromomethylbenzenesulfonamide is a chemical compound characterized by the presence of a benzene ring, a sulfonamide group, and a bromomethyl substituent. It is recognized for its unique chemical structure and reactivity, which makes it a versatile building block in the field of medicinal chemistry and drug discovery.

Uses

Used in Pharmaceutical and Agrochemical Industries:
3-Bromomethylbenzenesulfonamide is utilized as a reagent in organic synthesis reactions for the production of pharmaceuticals and agrochemicals. Its unique properties contribute to the development of new drugs and chemical compounds with potential applications in these industries.
Used as a Potent Antibiotic and Antifungal Agent:
3-Bromomethylbenzenesulfonamide is recognized for its potential as a potent antibiotic and antifungal agent. It is valuable in the development of new drugs that can combat bacterial and fungal infections, offering a promising avenue for research and treatment options.
Used in Drug Discovery and Medicinal Chemistry:
Due to its versatility and reactivity, 3-Bromomethylbenzenesulfonamide serves as a valuable tool in drug discovery and medicinal chemistry. It is employed in the creation of diverse molecular structures, aiding researchers in the design and synthesis of novel therapeutic agents.
Used in the Treatment of Various Medical Conditions:
3-Bromomethylbenzenesulfonamide has been investigated for its potential use in the treatment of various medical conditions. Its broad applicability and chemical properties make it a promising candidate for further research and development in the medical field.

InChI:InChI=1/C7H8BrNO2S/c8-5-6-2-1-3-7(4-6)12(9,10)11/h1-4H,5H2,(H2,9,10,11)

Upstream product

• 65-85-0 benzoic acid 
• 636-76-0 3-sulfamoylbenzoic acid 
• 4025-64-3 3-Carboxybenzenesulfonyl chloride 
• 220798-42-5 3-(hydroxymethyl)benzenesulfonamide 

Relevant articles and documents

INHIBITORS OF α-AMINO-β-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE

The present disclosure discloses compounds capable of modulating the activity of α-amino-β-carboxymuconic acid semialdehyde decarboxylase (ACMSD), which are useful for the prevention and/or the treatment of diseases and disorders associated with defects in NAD+ biosynthesis, e.g., metabolic disorders, neurodegenerative diseases, chronic inflammatory diseases, kidney diseases, and diseases associated with ageing. The present application also discloses pharmaceutical compositions comprising said compounds and the use of such compounds as a medicament.

NOVEL PIPERIDINE DERIVATIVE

The invention provides a compound of the following formula (1): wherein m, n, and p are independently an integer of 0 - 4, provided 3 ≤ m + n ≤ 8; X is nitrogen atom or a group of the formula: C-R15; Y is a substituted or unsubstituted aromatic group, etc.; R15, R1, R2, R3, R4 , R5, R6 and R7 are hydrogen atom, a substituted or unsubstituted alkyl group, etc.; and Z is hydrogen atom, cyano group, etc., or a prodrug thereof, or a pharmaceutically acceptable salt thereof, which exhibits an action for enhancing LDL receptor expression, and is useful as a medicament for treating hyperlipidemia, atherosclerosis, etc.